Evidence map›Paper›PMID 33777497›Full record

ArticleMRS communications2019

Piezoelectric BioMEMS Cantilever for Measurement of Muscle Contraction and for Actuation of Mechanosensitive Cells.

Elizabeth A Coln, Alisha Colon, Christopher J Long, Narasimhan Narasimhan Sriram, Mandy Esch, Jean-Matthieu Prot, Daniel H Elbrecht, Ying Wang, Max Jackson, Michael L Shuler and 1 more

Open access · greenAbstract read
In one paragraph

Article in MRS communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Fabrication and Biomedical Applications of Heart-on-a-chip.International journal of bioprinting · 2021
    Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Elizabeth A ColnHybrid Systems Laboratory, University of Central Florida, NanoScience Technology Center, 12424 Research Parkway, Suite 400, Orlando, FL 32826.
Alisha ColonHybrid Systems Laboratory, University of Central Florida, NanoScience Technology Center, 12424 Research Parkway, Suite 400, Orlando, FL 32826.
Christopher J LongHesperos, Inc., 3259 Progress Drive #158, Orlando, FL 32826.
Narasimhan Narasimhan SriramHesperos, Inc., 3259 Progress Drive #158, Orlando, FL 32826.
Mandy EschDepartment of Biomedical Engineering, Cornell University, Weill Hall, Ithaca, NY 14853.
Jean-Matthieu ProtDepartment of Biomedical Engineering, Cornell University, Weill Hall, Ithaca, NY 14853.
Daniel H ElbrechtHybrid Systems Laboratory, University of Central Florida, NanoScience Technology Center, 12424 Research Parkway, Suite 400, Orlando, FL 32826.
Ying WangDepartment of Biomedical Engineering, Cornell University, Weill Hall, Ithaca, NY 14853.
Max JacksonHesperos, Inc., 3259 Progress Drive #158, Orlando, FL 32826.
Michael L ShulerHesperos, Inc., 3259 Progress Drive #158, Orlando, FL 32826.
James J HickmanHybrid Systems Laboratory, University of Central Florida, NanoScience Technology Center, 12424 Research Parkway, Suite 400, Orlando, FL 32826.
Hesperos (United States) · USCornell University · USUniversity of Central Florida · US

Funding

Populating MPS database with data from multi-organ, human-on-a-chip microphysiological systemsR44TR001326 · NCATS · HESPEROS, LLC · PI HICKMAN, JAMES J, SHULER, MICHAEL L · 2016 to 2021
$6.5M
An In Vitro Model of Stem Cell Innervation of MyotubesR01NS050452 · NINDS · UNIVERSITY OF CENTRAL FLORIDA · PI HICKMAN, JAMES J · 2005 to 2020
$6.4M
NCATS NIH HHS R44 TR001326NINDS NIH HHS R01 NS050452
6 · The paper itself

Abstract

A piezoelectric biomedical microelectromechanical system (bioMEMS) cantilever device was designed and fabricated to act as either a sensing element for muscle tissue contraction or as an actuator to apply mechanical force to cells. The sensing ability of the piezoelectric cantilevers was shown by monitoring the electrical signal generated from the piezoelectric aluminum nitride in response to the contraction of iPSC-derived cardiomyocytes cultured on the piezoelectric cantilevers. Actuation was demonstrated by applying electrical pulses to the piezoelectric cantilever and observing bending via an optical detection method. This piezoelectric cantilever device was designed to be incorporated into body-on-a-chip systems.

Identifiers

PMID33777497
PMCPMC7995331
OpenAlexW2977206755

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.