ArticleSultan Qaboos University medical journal2021
The Potential of Light Microscopic Features of the Oral Mucosa in Predicting Post-mortem Interval.
Article in Sultan Qaboos University medical journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed, 7 citations in OpenAlex.
- Gingival Margin Damage During Supragingival Dental Polishing by Inexperienced Operator-Pilot Study.Journal of functional biomaterials · 2024Article
- Histogical changes in oral mucosa (gingiva) as a method for estimating post-mortem interval: A literature review.The Saudi dental journal · 2024Review
- A comparative evaluation of light microscopic features of normal oral mucosa and its time dependent autolytic changes in deceased individuals - An observational study.Journal of oral and maxillofacial pathology : JOMFPArticle
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe post-mortem interval (PMI) refers to the amount of time elapsed between death and discovery of the body. This study aimed to evaluate light microscopic cellular changes in the oral mucosa and identify the potential of this method for predicting PMI.
methodsThis prospective study was conducted between July 2016 and January 2018 at the Institute of Dental Sciences, Siksha 'O' Anusandhan University, Bhubaneswar, India. A total of 150 post-mortem (including 75 gingival and 75 buccal mucosa samples) and 40 ante-mortem (including 20 gingival and 20 buccal mucosa samples) tissue samples were compared using haematoxylin and eosin, periodic acid-Schiff (PAS) and van Gieson stains. Microscopic changes in the epithelium and connective tissue were categorised according to PMI stage as early (<12.5 hours since death), intermediate (12.5-20.5 hours since death) or late (>20.5 hours since death).
resultsMost epithelial cellular changes occurred early, except for arc-shaped nuclei and epithelial shredding which were intermediate and late changes, respectively. However, microscopic changes in the connective tissue were only observable at ≥12.5 hours. There was a progressive decrease in intensity in van Gieson stains and an increase in intensity in PAS stains as PMI increased. Several microscopic features were found to be significant predictors of PMI including epithelial homogenisation, cytoplasmic vacuolation, nuclear degeneration, arc-shaped nuclei, chromatin clumping, red blood cell clumping and lysis, melanin incontinency, myofibril degeneration, salivary gland
conclusionThese findings indicate that microscopic evaluation of the oral mucosa may be helpful for PMI prediction.
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