Evidence map›Paper›PMID 33777335›Full record

ArticleComputational and structural biotechnology journal2021

Functional and conformational impact of cancer-associated

Christine Canbezdi, Malcy Tarin, Alexandre Houy, Dorine Bellanger, Tatiana Popova, Marc-Henri Stern, Sergio Roman-Roman, Samar Alsafadi

Open access · goldAbstract read
In one paragraph

Article in Computational and structural biotechnology journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Role of alternative splicing in cancer progression.Irish journal of medical science · 2026
    Review
  3. Distinct and convergent effects ofProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. International journal of molecular sciences · 2023
    Article
  13. Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Christine CanbezdiInstitut Curie, PSL Research University, Uveal Melanoma Group, Translational Research Department, Paris, France.
Malcy TarinInstitut Curie, PSL Research University, Uveal Melanoma Group, Translational Research Department, Paris, France.
Alexandre HouyInstitut Curie, PSL Research University, INSERM U830, DNA Repair and Uveal Melanoma (D.R.U.M.), Paris, France.
Dorine BellangerInstitut Curie, PSL Research University, INSERM U830, DNA Repair and Uveal Melanoma (D.R.U.M.), Paris, France.
Tatiana PopovaInstitut Curie, PSL Research University, INSERM U830, DNA Repair and Uveal Melanoma (D.R.U.M.), Paris, France.
Marc-Henri SternInstitut Curie, PSL Research University, INSERM U830, DNA Repair and Uveal Melanoma (D.R.U.M.), Paris, France.
Sergio Roman-RomanInstitut Curie, PSL Research University, Uveal Melanoma Group, Translational Research Department, Paris, France.
Samar AlsafadiInstitut Curie, PSL Research University, Uveal Melanoma Group, Translational Research Department, Paris, France.
Université Paris Sciences et Lettres · FRInserm · FRUniversité de Tours · FR

Funding

NCI NIH HHS HHSN261201400008CNCI NIH HHS HHSN261201500003CNCI NIH HHS HHSN261201500003I
6 · The paper itself

Abstract

The hotspot mutations of

Indexed as

CancerFunctional impactIn-silico analysisMissense mutationsProtein conformationSF3B1Splicing

Identifiers

PMID33777335
PMCPMC7960499
OpenAlexW3135849203

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.