Evidence map›Paper›PMID 33777278›Full record

ArticleThe Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale2021

Chronic Hepatitis C Virus Infection Modulates the Transcriptional Profiles of CD4

Michal Holub, Alžběta Stráníková, Ondřej Beran, Simona Arientová, Oldřich Bartoš, Kateřina Kondelková, Stanislav Plíšek, Pavel Chalupa

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 55% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Michal HolubDepartment of Infectious Diseases, First Faculty of Medicine, Charles University and Military University Hospital Prague, U Vojenské Nemocnice 1200, Praha 6 169 02, Czech Republic.ORCID https://orcid.org/0000-0003-1894-2605
Alžběta StráníkováDepartment of Infectious Diseases, First Faculty of Medicine, Charles University and Military University Hospital Prague, U Vojenské Nemocnice 1200, Praha 6 169 02, Czech Republic.
Ondřej BeranDepartment of Infectious Diseases, First Faculty of Medicine, Charles University and Military University Hospital Prague, U Vojenské Nemocnice 1200, Praha 6 169 02, Czech Republic.
Simona ArientováDepartment of Infectious Diseases, First Faculty of Medicine, Charles University and Military University Hospital Prague, U Vojenské Nemocnice 1200, Praha 6 169 02, Czech Republic.
Oldřich BartošDepartment of Infectious Diseases, First Faculty of Medicine, Charles University and Military University Hospital Prague, U Vojenské Nemocnice 1200, Praha 6 169 02, Czech Republic.
Kateřina KondelkováInstitute of Clinical Immunology, Faculty of Medicine in Hradec Králové, Charles University, Sokolská 581, Hradec Králové 500 05, Czech Republic.
Stanislav PlíšekDepartment of Infectious Diseases, Faculty of Medicine, Charles University and University Hospital, Sokolská 581, Hradec Králové 500 05, Czech Republic.
Pavel ChalupaDepartment of Infectious and Tropical Diseases, First Faculty of Medicine, Charles University and University Hospital Bulovka, Budínova 2, Praha 8 180 81, Czech Republic.
Charles University · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChronic hepatitis C (CHC) is associated with altered cell-mediated immune response.

objectiveThe aim of the study was to characterize functional alterations in CD4

resultThe patients with CHC had significantly lower percentages of CD4

conclusionChronic HCV infection is associated with downregulation of TFs Gata3 and Ror

Identifiers

PMID33777278
PMCPMC7979312
OpenAlexW3139057935

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.