Evidence map›Paper›PMID 33777274›Full record

ArticlePrzeglad gastroenterologiczny2020

Usefulness of the hydrogen breath test in patients with functional dyspepsia.

Cezary Chojnacki, Paulina Konrad, Aleksandra Błońska, Jan Chojnacki, Marta Mędrek-Socha

Open access · goldAbstract read
In one paragraph

Article in Przeglad gastroenterologiczny, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. World journal of clinical cases · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Cezary ChojnackiDepartment of Clinical Nutrition and Gastroenterological Diagnostics, Medical University of Lodz, Lodz, Poland.
Paulina KonradDepartment of Clinical Nutrition and Gastroenterological Diagnostics, Medical University of Lodz, Lodz, Poland.
Aleksandra BłońskaDepartment of Clinical Nutrition and Gastroenterological Diagnostics, Medical University of Lodz, Lodz, Poland.
Jan ChojnackiDepartment of Clinical Nutrition and Gastroenterological Diagnostics, Medical University of Lodz, Lodz, Poland.
Marta Mędrek-SochaDepartment of Clinical Nutrition and Gastroenterological Diagnostics, Medical University of Lodz, Lodz, Poland.
Medical University of Lodz · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe pathogenesis of functional dyspepsia is complex and not well understood. Therefore, in this disease there should be considered involvement of different pathogenic factors, including intestinal bacteria.

aimTo evaluate the results of the hydrogen breath test in relation to the clinical picture of functional dyspepsia. MATERIAL AND

methodsThe study included 40 healthy subjects (group I), 72 patients with postprandial distress syndrome (PDS, group II), and 84 patients with epigastric pain syndrome (EPS, group III). The diagnosis of functional dyspepsia was based on Rome Criteria IV. The urea breath test (13C-UBT) and lactulose hydrogen breath test (LHBT) were performed in all subjects. Patients with a positive urea breath test were excluded from the study. Patients with a positive LHBT test were assigned to antibiotic therapy (1200 mg daily for 14 days). Before treatment and 6 weeks after the end of antibiotic therapy the LHBT was performed, and severity of dyspeptic symptoms was assessed using a 10-points visual analogue scale.

resultsA positive LHBT test was found in 35 (48.6%) patients in the group with PDS, and in 40 (47.6%) patients with EPS (

conclusionsQuantitative and/or qualitative changes in the gut microbiota may be the cause of functional dyspepsia.

Indexed as

bacterial overgrowthfunctional dyspepsiarifaximin

Identifiers

PMID33777274
PMCPMC7988826
OpenAlexW3007666561

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.