Evidence map›Paper›PMID 33777270›Full record

ArticlePrzeglad gastroenterologiczny2020

The risk of small bowel adenocarcinoma in patients with Crohn's disease.

Gustaw Lech, Wojciech Korcz, Emilia Kowalczyk, Andrzej Chaber, Maciej Słodkowski

Open access · goldAbstract read
In one paragraph

Article in Przeglad gastroenterologiczny, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Gustaw LechDepartment of General, Gastroenterological, and Oncological Surgery, Medical University of Warsaw, Warsaw, Poland.
Wojciech KorczDepartment of General, Gastroenterological, and Oncological Surgery, Medical University of Warsaw, Warsaw, Poland.
Emilia KowalczykStudent Science Group at Department of General, Gastroenterological, and Oncological Surgery, Medical University of Warsaw, Warsaw, Poland.
Andrzej ChaberDepartment of General, Gastroenterological, and Oncological Surgery, Medical University of Warsaw, Warsaw, Poland.
Maciej SłodkowskiDepartment of General, Gastroenterological, and Oncological Surgery, Medical University of Warsaw, Warsaw, Poland.
Medical University of Warsaw · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionSmall bowel adenocarcinoma (SBA) is an unusual complication of Crohn's disease (CD).

aimTo describe the incidence rate, clinical features, and outcomes of SBA in a group of subsequent patients with CD. MATERIAL AND

methodsWe retrospectively analysed outpatient and hospital records and identified a group of patients with diagnosed CD. Then we reviewed all medical records of patients who reported for follow-up visits in a 14-year period. We identified a group of 103 patients, whose medical records were evaluated for the presence of SBA.

resultsLong-term follow-up carried out in the group of consecutively treated patients with CD revealed an 0.97% incidence rate of SBA. Cancer was located in the ileum and the clinical presentation was subileus and anaemia. The patient underwent ileocaecal resection, and the postoperative period was uneventful.

conclusionsSBA is a rare complication of CD. Although the authors are aware that the number of patients enrolled in the study is insufficient to draw far-reaching conclusions, the results obtained are significant for determination of the incidence rate of SBA in the Caucasian population of patients with CD. The key issue of effective treatment of patients with SBA was early detection of the lesion and R0 resection with proper lymphadenectomy. However, it is worth noting that in more advanced stages of SBA the future belongs to, and outcome improvement depends on, new regimes of adjuvant personalised chemotherapies. Further studies on the mechanisms of carcinogenesis in patients with CD are essential.

Indexed as

bowelcancerCrohn’s diseaseinflammatory bowel diseasesmall bowel adenocarcinoma

Identifiers

PMID33777270
PMCPMC7988828
OpenAlexW3112684014

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.