Evidence map›Paper›PMID 33776938›Full record

ArticleFrontiers in endocrinology2021

Advances in Detecting Low Prevalence Somatic

Vitor Rodrigues da Costa, Larissa Valdemarin Bim, Luiza Dornelles Penteado Pacheco E Silva, Gabriel Avelar Colloza-Gama, André Uchimura Bastos, Rosana Delcelo, Gisele Oler, Janete Maria Cerutti

Open access · goldAbstract read
In one paragraph

Article in Frontiers in endocrinology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Vitor Rodrigues da CostaGenetic Bases of Thyroid Tumors Laboratory, Department of Morphology and Genetics, Division of Genetics, Universidade Federal de São Paulo, São Paulo, Brazil.
Larissa Valdemarin BimGenetic Bases of Thyroid Tumors Laboratory, Department of Morphology and Genetics, Division of Genetics, Universidade Federal de São Paulo, São Paulo, Brazil.
Luiza Dornelles Penteado Pacheco E SilvaGenetic Bases of Thyroid Tumors Laboratory, Department of Morphology and Genetics, Division of Genetics, Universidade Federal de São Paulo, São Paulo, Brazil.
Gabriel Avelar Colloza-GamaGenetic Bases of Thyroid Tumors Laboratory, Department of Morphology and Genetics, Division of Genetics, Universidade Federal de São Paulo, São Paulo, Brazil.
André Uchimura BastosGenetic Bases of Thyroid Tumors Laboratory, Department of Morphology and Genetics, Division of Genetics, Universidade Federal de São Paulo, São Paulo, Brazil.
Rosana DelceloDepartment of Pathology, Universidade Federal de São Paulo, São Paulo, Brazil.
Gisele OlerGenetic Bases of Thyroid Tumors Laboratory, Department of Morphology and Genetics, Division of Genetics, Universidade Federal de São Paulo, São Paulo, Brazil.
Janete Maria CeruttiGenetic Bases of Thyroid Tumors Laboratory, Department of Morphology and Genetics, Division of Genetics, Universidade Federal de São Paulo, São Paulo, Brazil.
Universidade Federal de São Paulo · BRUniversidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Two recurrent Methods: DNA was isolated from formalin-fixed paraffin-embedded (FFPE) specimens from 89 PTC and 40 paired lymph node metastases. The prevalence of the hot spot Results: In general, 16 out of 89 (18%) PTC samples and 14 out of 40 (35%) lymph node metastases harbored Conclusion: This study observed a good concordance among the methodologies used to detect

Indexed as

MutationPromoter Regions, GeneticAllelesDNAFalse Negative ReactionsGenotypeHumansLymphatic MetastasisPolymorphism, Single NucleotidePrevalencePrognosisReproducibility of ResultsSequence Analysis, DNATelomeraseThyroid Cancer, PapillaryThyroid NeoplasmsDNATelomeraseTERT protein, humanC228TC250Tdroplet digital PCRPapillary thyroid carcinomaTaqMan allele discrimination assayTERT (telomerase reverse transcriptase)

Identifiers

PMID33776938
PMCPMC7994758
OpenAlexW3139444859

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.