ReviewFrontiers in neurology2021
Ictal and Interictal Cardiac Manifestations in Epilepsy. A Review of Their Relation With an Altered Central Control of Autonomic Functions and With the Risk of SUDEP.
Review in Frontiers in neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 47 citations in OpenAlex.
- Electrocardiographic abnormalities in epilepsy: analysis of cardiac conduction patterns and SUDEP Risk.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025Pooled it
- Drug-resistant epilepsy and mortality-Why and when do neuromodulation and epilepsy surgery reduce overall mortality.Epilepsia · 2022Pooled it
- Dynamic alterations in cardiac autonomic regulation during recurrent generalized seizures.iScience · 2026Article
- qEEG and Functional Connectivity as a Translational Bridge Between Humans and Dogs in Epilepsy and Associated Disorders: From Spontaneous Model to Automatic Classification-An Integrative Review.Veterinary sciences · 2026Review
- Death in Epilepsy: Ictogenic Vs. Cardiogenic Mechanisms and Immunoassays in Postmortem Interval Estimation - Case Report.Maedica · 2026Article
- Subclinical cardiac dysfunction detected by speckle-tracking echocardiography in children with drug-resistant epilepsy.Pediatric research · 2026Article
- Intersection of epilepsy and cardiac health: Insights from electrocardiography and syndromic associations.Epilepsia · 2025Review
- Ictal asystole and ictal syncope must be differentiated from neurally mediated syncope.Epileptic disorders : international epilepsy journal with videotape · 2025Article
- Sudden unexpected death in epilepsy: respiratory vs. cardiac contributions.Cardiovascular research · 2025Review
- An interesting case of subacute sclerosing panencephalitis presenting with Balint's syndrome and dysautonomia.Encephalitis (Seoul, Korea) · 2025Article
- Cardiac manifestations of prolonged seizure: A case report on reverse takotsubo syndrome and neurogenic stunned myocardium.Radiology case reports · 2025Article
- Electro-Clinical Features and Functional Connectivity Analysis in SYN1-Related Epilepsy.Annals of neurology · 2024Article
- Heart Rate Variability as a Tool for Seizure Prediction: A Scoping Review.Journal of clinical medicine · 2024Article
- Aborted sudden cardiac death in a young patient with epilepsy and the Gorlin Goltz syndrome.Epilepsy & behavior reports · 2024Article
- Mapping of Neuro-Cardiac Electrophysiology: Interlinking Epilepsy and Arrhythmia.Journal of cardiovascular development and disease · 2023Review
- Exploring Autonomic Alterations during Seizures in Temporal Lobe Epilepsy: Insights from a Heart-Rate Variability Analysis.Journal of clinical medicine · 2023Article
- Review
- ECG-Based Semi-Supervised Anomaly Detection for Early Detection and Monitoring of Epileptic Seizures.International journal of environmental research and public health · 2023Article
- Simultaneous Determination of Lamotrigine, Oxcarbazepine, Lacosamide, and Topiramate in Rat Plasma by Ultra-Performance Liquid Chromatography-Tandem Mass Spectrometry.International journal of analytical chemistry · 2022Article
- COVID-19 prevalence and mortality in people with epilepsy: A nation-wide multicenter study.Epilepsy & behavior : E&B · 2021Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There is a complex interrelation between epilepsy and cardiac pathology, with both acute and long-term effects of seizures on the regulation of the cardiac rhythm and on the heart functioning. A specific issue is the potential relation between these cardiac manifestations and the risk of Sudden and Unexpected Death in Epilepsy (SUDEP), with unclear respective role of centrally-control ictal changes, long-term epilepsy-related dysregulation of the neurovegetative control and direct effects on the heart function. In the present review, we detailed available data about ictal cardiac changes, along with interictal cardiac manifestations associated with long-term functional and structural alterations of the heart. Pathophysiological mechanisms of these cardiac changes are discussed, with a specific focus on central mechanisms and the investigation of a possible deregulation of the central control of autonomic functions in addition to the role of catecholamine and hypoxemia on heart.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.