Evidence map›Paper›PMID 33776890›Full record

ReviewFrontiers in neurology2021

The Multi-Partner Consortium to Expand Dementia Research in Latin America (ReDLat): Driving Multicentric Research and Implementation Science.

Agustin Ibanez, Jennifer S Yokoyama, Katherine L Possin, Diana Matallana, Francisco Lopera, Ricardo Nitrini, Leonel T Takada, Nilton Custodio, Ana Luisa Sosa Ortiz, José Alberto Avila-Funes and 25 more

Abstract readReview
In one paragraph

Review in Frontiers in neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 89 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
89citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

89 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Article
  6. Article
  7. Linking the exposome to the brain-behaviour phenotype.Nature reviews. Neuroscience · 2026
    Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Emerging directions in tauopathy research.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Neural embedding of frailty in cognitively unimpaired aging and dementia across Latin America.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
  18. Benchmarking speech biomarkers of Alzheimer's against cognitive and neural measures.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
  19. The landscape of dementia research, diagnosis, treatment, and care in Latin America.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Review
  20. Article

29 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

35 authors.

Agustin IbanezThe Global Brain Health Institute (GBHI), University of California, San Francisco, San Francisco, CA, United States.
Jennifer S YokoyamaThe Global Brain Health Institute (GBHI), University of California, San Francisco, San Francisco, CA, United States.
Katherine L PossinThe Global Brain Health Institute (GBHI), University of California, San Francisco, San Francisco, CA, United States.
Diana MatallanaPsychiatry Department, School of Medicine, Aging Institute, Pontificia Universidad Javeriana, Bogotá, Colombia.
Francisco LoperaGrupo de Neurociencias de Antioquia, Universidad de Antioquia, Medellín, Colombia.
Ricardo NitriniCognitive and Behavioral Neurology Unit, Hospital das Clinicas, University of São Paulo Medical School, São Paulo, Brazil.
Leonel T TakadaCognitive and Behavioral Neurology Unit, Hospital das Clinicas, University of São Paulo Medical School, São Paulo, Brazil.
Nilton CustodioUnit Cognitive Impairment and Dementia Prevention, Cognitive Neurology Center, Peruvian Institute of Neurosciences, Lima, Perú.
Ana Luisa Sosa OrtizInstituto Nacional de Neurologia y Neurocirugia MVS, Universidad Nacional Autonoma de Mexico, Mexico, Mexico.
José Alberto Avila-FunesDepartment of Geriatrics, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico, Mexico.
Maria Isabel BehrensCentro de Investigación Clínica Avanzada, Hospital Clínico, Facultad de Medicina Universidad de Chile, Santiago, Chile.
Andrea SlachevskyClínica Alemana Santiago, Universidad del Desarrollo, Santiago, Chile.
Richard M MyersHudson Alpha Institute for Biotechnology, Huntsville, AL, United States.
J Nicholas CochranHudson Alpha Institute for Biotechnology, Huntsville, AL, United States.
Luis Ignacio BruscoFacultad de Medicina, Universidad de Buenos Aires, Buenos Aires, Argentina.
Martin A BrunoNational Scientific and Technical Research Council (CONICET), Buenos Aires, Argentina.
Sonia M D BruckiCognitive and Behavioral Neurology Unit, Hospital das Clinicas, University of São Paulo Medical School, São Paulo, Brazil.
Stefanie Danielle Pina-EscuderoThe Global Brain Health Institute (GBHI), University of California, San Francisco, San Francisco, CA, United States.
Maira Okada de OliveiraThe Global Brain Health Institute (GBHI), University of California, San Francisco, San Francisco, CA, United States.
Patricio Donnelly KehoeNational Scientific and Technical Research Council (CONICET), Buenos Aires, Argentina.
Adolfo M GarciaThe Global Brain Health Institute (GBHI), University of California, San Francisco, San Francisco, CA, United States.
Juan Felipe CardonaUniversidad del Valle, Cali, Colombia.
Hernando Santamaria-GarciaMemory and Cognition Clinic, Intellectus, Hospital Universitario San Ignacio, Bogotá, Colombia.
Sebastian MoguilnerThe Global Brain Health Institute (GBHI), University of California, San Francisco, San Francisco, CA, United States.
Claudia Duran-AniotzSchool of Psychology, Center for Social and Cognitive Neuroscience, Latin American Institute for Brain Health (BrainLat), Universidad Adolfo Ibanez, Adolfo Ibanez University, Santiago, Chile.
Enzo TagliazucchiDepartamento de Física, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires, Argentina.
Marcelo MaitoCognitive Neuroscience Center, Universidad de San Andrés, Buenos Aires, Argentina.
Erika Mariana Longoria IbarrolaDepartment of Geriatrics, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico, Mexico.
Maritza Pintado-CaipaThe Global Brain Health Institute (GBHI), University of California, San Francisco, San Francisco, CA, United States.
Maria Eugenia GodoyCognitive Neuroscience Center, Universidad de San Andrés, Buenos Aires, Argentina.
Vera BakmanThe Global Brain Health Institute (GBHI), University of California, San Francisco, San Francisco, CA, United States.
Shireen JavandelDepartment of Neurology, Memory and Aging Center, University of California, San Francisco, San Francisco, CA, United States.
Kenneth S KosikDepartment of Molecular, Cellular, and Developmental Biology, Neuroscience Research Institute, University of California, Santa Barbara, Santa Barbara, CA, United States.
Victor ValcourThe Global Brain Health Institute (GBHI), University of California, San Francisco, San Francisco, CA, United States.
Bruce L MillerThe Global Brain Health Institute (GBHI), University of California, San Francisco, San Francisco, CA, United States.

Funding

US-South American Initiative for Genetic-Neural-Behavioral Interactions in Human Neurodegenerative ResearchR01AG057234 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Claudia Duran-Aniotz, Agustin M. Ibanez · 2019 to 2026
$6.1M
The UCSF Brain Health Assessment for the Detection of Cognitive Impairment Among Diverse Populations in Primary CareUH3NS105557 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI POSSIN, KATHERINE LAUREL · 2019 to 2021
$4.9M
Elucidating clinical heterogeneity in early-onset AD via genomics, transcriptomics, and neuroimagingR01AG062588 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI YOKOYAMA, JENNIFER S · 2019 to 2023
$4.0M
The complex interaction between Alzheimer drivers and agingRF1AG062479 · NIA · UNIVERSITY OF CALIFORNIA SANTA BARBARA · PI KOSIK, KENNETH STEPHEN · 2020 to 2020
$2.6M
NIA NIH HHS R01 AG057234NIA NIH HHS R01 AG062588NINDS NIH HHS UH3 NS105557
6 · The paper itself

Abstract

Dementia is becoming increasingly prevalent in Latin America, contrasting with stable or declining rates in North America and Europe. This scenario places unprecedented clinical, social, and economic burden upon patients, families, and health systems. The challenges prove particularly pressing for conditions with highly specific diagnostic and management demands, such as frontotemporal dementia. Here we introduce a research and networking initiative designed to tackle these ensuing hurdles, the Multi-partner consortium to expand dementia research in Latin America (ReDLat). First, we present ReDLat's regional research framework, aimed at identifying the unique genetic, social, and economic factors driving the presentation of frontotemporal dementia and Alzheimer's disease in Latin America relative to the US. We describe ongoing ReDLat studies in various fields and ongoing research extensions. Then, we introduce actions coordinated by ReDLat and the Latin America and Caribbean Consortium on Dementia (LAC-CD) to develop culturally appropriate diagnostic tools, regional visibility and capacity building, diplomatic coordination in local priority areas, and a knowledge-to-action framework toward a regional action plan. Together, these research and networking initiatives will help to establish strong cross-national bonds, support the implementation of regional dementia plans, enhance health systems' infrastructure, and increase translational research collaborations across the continent.

Indexed as

Alzheimer's diseasedementiafronto-temporal dementiageneticsimplementation scienceLatin AmericaSDOHSES

Identifiers

PMID33776890
PMCPMC7992978

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.