Evidence map›Paper›PMID 33776885›Full record

ArticleFrontiers in neurology2021

A Case Report of Central Nervous System Graft-Versus-Host Disease and Literature Review.

Mingming Li, Yue Zhang, Yujia Guan, Zunwei Zhang, Hanbing Dong, Yang Zhao, Hui Deng

Abstract readCase Reports
In one paragraph

Article in Frontiers in neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Acute Graft-Frontiers in immunology · 2021
    Review
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mingming LiDepartment of Neurology, First Affiliated Hospital of Jilin University, Changchun, China.
Yue ZhangDepartment of Neurology, First Affiliated Hospital of Jilin University, Changchun, China.
Yujia GuanDepartment of Neurology, First Affiliated Hospital of Jilin University, Changchun, China.
Zunwei ZhangDepartment of Neurology, First Affiliated Hospital of Jilin University, Changchun, China.
Hanbing DongDepartment of Neurology, First Affiliated Hospital of Jilin University, Changchun, China.
Yang ZhaoDepartment of Neurology, First Affiliated Hospital of Jilin University, Changchun, China.
Hui DengDepartment of Neurology, First Affiliated Hospital of Jilin University, Changchun, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As an adverse immune phenomenon, graft-versus-host disease often occurs after allogeneic hematopoietic stem cell transplantation. The incidence of acute and chronic graft-versus-host disease is about 40-60% and the mortality rate can reach 15%, which is a potentially fatal disease. There are rare GvHD cases involving the central nervous system. We reported a rare case of diffuse white matter changes after haploid bone marrow transplantation, summarizing its clinical manifestations and diagnosis and treatment in conjunction with the literature.

Indexed as

bone marrow transplantationcentral nervous systemdiffuse white matter lesionsgraft-versus-host diseaseimmunosuppression

Identifiers

PMID33776885
PMCPMC7987907

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.