Evidence map›Paper›PMID 33776875›Full record

ArticleFrontiers in neurology2021

Detection of Wandering Behaviors Using a Body-Worn Inertial Sensor in Patients With Cognitive Impairment: A Feasibility Study.

Rebecca J Kamil, Dara Bakar, Matthew Ehrenburg, Eric X Wei, Alexandra Pletnikova, Grace Xiao, Esther S Oh, Martina Mancini, Yuri Agrawal

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 4 pooled it
7.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 4 syntheses or guidelines pooled it, 26 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Rebecca J KamilDepartment of Otolaryngology-Head and Neck Surgery, Johns Hopkins University, Baltimore, MD, United States.
Dara BakarDepartment of Otolaryngology-Head and Neck Surgery, Johns Hopkins University, Baltimore, MD, United States.
Matthew EhrenburgDepartment of Otolaryngology-Head and Neck Surgery, Johns Hopkins University, Baltimore, MD, United States.
Eric X WeiJohns Hopkins University School of Medicine, Baltimore, MD, United States.
Alexandra PletnikovaDivision of Geriatric Medicine and Gerontology, Department of Medicine, Johns Hopkins University, Baltimore, MD, United States.
Grace XiaoDepartment of Otolaryngology-Head and Neck Surgery, Johns Hopkins University, Baltimore, MD, United States.
Esther S OhDivision of Geriatric Medicine and Gerontology, Department of Medicine, Johns Hopkins University, Baltimore, MD, United States.
Martina ManciniDepartment of Neurology, Oregon Health and Science University, School of Medicine, Portland, OR, United States.
Yuri AgrawalDepartment of Otolaryngology-Head and Neck Surgery, Johns Hopkins University, Baltimore, MD, United States.
Johns Hopkins University · USBrown University · USOregon Health & Science University · US

Funding

Research Education ComponentP30AG066507 · NIA · JOHNS HOPKINS UNIVERSITY · PI Corinne Pettigrew · 2020 to 2026
$29.3M
Age-related Changes in the Vestibular System and Functional ImplicationsK23DC013056 · NIDCD · JOHNS HOPKINS UNIVERSITY · PI AGRAWAL, YURI · 2014 to 2018
$1.2M
CSF predictors of postoperative delirium in non-demented hip fracture patientsK23AG043504 · NIA · JOHNS HOPKINS UNIVERSITY · PI OH, ESTHER SEUNGHEE · 2012 to 2016
$819k
NIA NIH HHS K23 AG043504NIA NIH HHS P30 AG066507NIDCD NIH HHS K23 DC013056
6 · The paper itself

Abstract

Patients with Alzheimer's disease (AD) and AD related dementias (ADRD) often experience spatial disorientation that can lead to wandering behavior, characterized by aimless or purposeless movement. Wandering behavior has been associated with falls, caregiver burden, and nursing home placement. Despite the substantial clinical consequences of wandering, there is currently no standardized approach to objectively quantify wandering behavior. In this pilot feasibility study, we used a lightweight inertial sensor to examine mobility characteristics of a small group of 12 older adults with ADRD and mild cognitive impairment in their homes. Specifically, we evaluated their compliance with wearing a sensor for a minimum of 4 days. We also examined the ability of the sensor to measure turning frequency and direction changes, given that frequent turns and direction changes during walking have been observed in patients who wander. We found that all patients were able to wear the sensor yielding quantitative turn data including number of turns over time, mean turn duration, mean peak turn speed, and mean turn angle. We found that wanderers make more frequent, quicker turns compared to non-wanderers, which is consistent with pacing or lapping behavior. This study provides preliminary evidence that continuous monitoring in patients with dementia is feasible using a wearable sensor. More studies are needed to explore if objective measures of turning behaviors collected using inertial sensors can be used to identify wandering behavior.

Indexed as

body-worn inertial sensorcognitive impairmentdementiaturningwandering behavior

Identifiers

PMID33776875
PMCPMC7991404
OpenAlexW3138157974

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.