ReviewFrontiers in psychiatry2021
The Auditory Steady-State Response: Electrophysiological Index for Sensory Processing Dysfunction in Psychiatric Disorders.
Review in Frontiers in psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
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Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Neurotransmitters in Auditory Processing Disorders and Neurodevelopmental Disorders: A Common Neurobiological Substrate?Children (Basel, Switzerland) · 2026Review
- Identifying biomarkers of neurodevelopmental and mental health outcomes in a prospective longitudinal cohort of South African children: design and feasibility of the Safe Passage BONO study.Pilot and feasibility studies · 2026Article
- Transdiagnostic Profiles of BOLD Signal Variability in Autism and Schizophrenia Spectrum Disorders: Associations With Cognition and Functioning.Human brain mapping · 2026Article
- Article
- Applications and potential mechanisms of transcranial magnetic stimulation in autism spectrum disorders.Journal of translational medicine · 2026Review
- Walking Modulates Active Auditory Sensing.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- The Application of Gamma-Range Auditory Steady-State Responses in Animal Models: A Semi-Structured Literature Review.Brain sciences · 2025Review
- Objective Detection of Auditory Steady-State Responses (ASSRs) Based on Mutual Information: Receiver Operating Characteristics and Performance Across Modulation Rates and Levels.Audiology research · 2025Article
- Deviation from Nash mixed equilibrium in repeated rock-scissors-paper reflect individual traits.Scientific reports · 2025Article
- Auditory steady-state response deficits in Fragile X Syndrome implicate deficits in stimulus representation maintenance and GABAergic modulation.medRxiv : the preprint server for health sciences · 2025Article
- Neurophysiological Signatures of Major Depressive Disorder and Frontocentral Gamma Auditory Response Deficits.Depression and anxiety · 2025Article
- Prefrontal Excitation/ Inhibition Balance Supports Adolescent Enhancements in Circuit Signal to Noise Ratio.bioRxiv : the preprint server for biology · 2024Article
- Network resonance and the auditory steady state response.Scientific reports · 2024Article
- Transcranial Alternating Current Stimulation Alters Auditory Steady-State Oscillatory Rhythms and Their Cross-Frequency Couplings.Clinical EEG and neuroscience · 2024Article
- Gamma Oscillations and Potassium Channel Modulation in Schizophrenia: Targeting GABAergic Dysfunction.Clinical EEG and neuroscience · 2024Article
- Effects of Memantine on the Auditory Steady-State and Harmonic Responses to 40 Hz Stimulation Across Species.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2024Article
- The Thalamocortical Mechanism Underlying the Generation and Regulation of the Auditory Steady-State Responses in Awake Mice.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Auditory Biomarkers of Neuropsychiatric Disorders in Nonhuman Primates.Advances in neurobiology · 2024Review
- Detecting Central Auditory Processing Disorders in Awake Mice.Brain sciences · 2023Article
Corrections and comments
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sensory processing is disrupted in several psychiatric disorders, including schizophrenia, bipolar disorder, and autism spectrum disorder. In this review, we focus on the electrophysiological auditory steady-state response (ASSR) driven by high-frequency stimulus trains as an index for disease-associated sensory processing deficits. The ASSR amplitude is suppressed within the gamma band (≥30 Hz) among these patients, suggesting an imbalance between GABAergic and N-methyl-D-aspartate (NMDA) receptor-mediated neurotransmission. The reduced power and synchronization of the 40-Hz ASSR are robust in patients with schizophrenia. In recent years, similar ASSR deficits at gamma frequencies have also been reported in patients with bipolar disorder and autism spectrum disorder. We summarize ASSR abnormalities in each of these psychiatric disorders and suggest that the observed commonalities reflect shared pathophysiological mechanisms. We reviewed studies on phase resetting in which a salient sensory stimulus affects ASSR. Phase resetting induces the reduction of both the amplitude and phase of ASSR. Moreover, phase resetting is also affected by rare auditory stimulus patterns or superimposed stimuli of other modalities. Thus, sensory memory and multisensory integration can be investigated using phase resetting of ASSR. Here, we propose that ASSR amplitude, phase, and resetting responses are sensitive indices for investigating sensory processing dysfunction in psychiatric disorders.
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