Evidence map›Paper›PMID 33776813›Full record

ReviewFrontiers in psychiatry2021

Neuroimaging as a Window Into the Pathophysiological Mechanisms of Schizophrenia.

Nina Vanessa Kraguljac, Adrienne Carol Lahti

Abstract readReview
In one paragraph

Review in Frontiers in psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. The thalamus in psychosis spectrum disorder.Frontiers in neuroscience · 2023
    Article
  7. Review
  8. Article
  9. Article
  10. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Nina Vanessa KraguljacNeuroimaging and Translational Research Laboratory, Department of Psychiatry and Behavioral Neurobiology, University of Alabama at Birmingham, Birmingham, AL, United States.
Adrienne Carol LahtiNeuroimaging and Translational Research Laboratory, Department of Psychiatry and Behavioral Neurobiology, University of Alabama at Birmingham, Birmingham, AL, United States.

Funding

Trajectories of treatment response as window into the heterogeneity of psychosis: a longitudinal multimodal imaging study in medication-naieve first episode psychosis patientsR01MH113800 · NIMH · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI LAHTI, ADRIENNE C · 2018 to 2022
$3.9M
Contribution of Glutamate Excess and Inflammation to Progressive White Matter Changes in PsychosisR01MH118484 · NIMH · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI KRAGULJAC, NINA VANESSA · 2019 to 2023
$3.3M
Glutamate, brain connectivity and duration of untreated psychosisR01MH102951 · NIMH · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI LAHTI, ADRIENNE C · 2014 to 2018
$2.9M
NIMH NIH HHS R01 MH102951NIMH NIH HHS R01 MH113800NIMH NIH HHS R01 MH118484
6 · The paper itself

Abstract

Schizophrenia is a complex neuropsychiatric disorder with a diverse clinical phenotype that has a substantial personal and public health burden. To advance the mechanistic understanding of the illness, neuroimaging can be utilized to capture different aspects of brain pathology

Indexed as

antipsychotic naïvediffusion weighted imagingduration of untreated psychosisfirst episode psychosisfunctional MRImagnetic resonance spectroscopypharmacological challengetreatment response

Identifiers

PMID33776813
PMCPMC7991588

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.