Evidence map›Paper›PMID 33776650›Full record

ArticleFrontiers in cellular neuroscience2021

Potentiation of Brain-Derived Neurotrophic Factor-Induced Protection of Spiral Ganglion Neurons by C3 Exoenzyme/Rho Inhibitor.

Jennifer Harre, Laura Heinkele, Melanie Steffens, Athanasia Warnecke, Thomas Lenarz, Ingo Just, Astrid Rohrbeck

Erratum issuedOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cellular neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 57% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Jennifer Harre *Department of Otorhinolaryngology, Head and Neck Surgery, Hannover Medical School, Hannover, Germany.
Laura Heinkele *Department of Otorhinolaryngology, Head and Neck Surgery, Hannover Medical School, Hannover, Germany.
Melanie SteffensDepartment of Otorhinolaryngology, Head and Neck Surgery, Hannover Medical School, Hannover, Germany.
Athanasia WarneckeDepartment of Otorhinolaryngology, Head and Neck Surgery, Hannover Medical School, Hannover, Germany.
Thomas LenarzDepartment of Otorhinolaryngology, Head and Neck Surgery, Hannover Medical School, Hannover, Germany.
Ingo JustInstitute of Toxicology, Hannover Medical School, Hannover, Germany.
Astrid RohrbeckInstitute of Toxicology, Hannover Medical School, Hannover, Germany.
Medizinische Hochschule Hannover · DEDeutsche Forschungsgemeinschaft · DEHearing4all · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Preservation of the excitability of spiral ganglion neurons (SGN) may contribute to an improved speech perception after cochlear implantation. Thus, the application of exogenous neurotrophic factors such as the neurotrophin brain-derived neurotrophic factor (BDNF) to increase SGN survival

Indexed as

brain-derived neurotrophic factorC3 exoenzymeneuroprotectionRhoAspiral ganglion neurons

Identifiers

PMID33776650
PMCPMC7991574
OpenAlexW3135667057

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.