Evidence map›Paper›PMID 33776614›Full record

ArticleAdvanced functional materials2021

Hybrid Graphene-Gold Nanoparticle-based Nucleic Acid Conjugates for Cancer-Specific Multimodal Imaging and Combined Therapeutics.

Letao Yang, Tae-Hyung Kim, Hyeon-Yeol Cho, Jeffrey Luo, Jong-Min Lee, Sy-Tsong Dean Chueng, Yannan Hou, Perry To-Tien Yin, Jiyou Han, Jong Hoon Kim and 3 more

Open access · greenAbstract read
In one paragraph

Article in Advanced functional materials, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 88 citations in OpenAlex.

  1. Article
  2. FeRSC advances · 2026
    Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Review
  12. Oral delivery of RNAi for cancer therapy.Cancer metastasis reviews · 2023
    Review
  13. Article
  14. Design and Synthesis of SERS Materials for In Vivo Molecular Imaging and Biosensing.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
    Review
  15. Article
  16. Article
  17. Article
  18. Carbon nanomaterials for phototherapy.Nanophotonics (Berlin, Germany) · 2022
    Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 3 countries.

Letao YangDepartment of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey, 123 Bevier Road, Piscataway, NJ 08854, USA.
Tae-Hyung KimDepartment of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey, 123 Bevier Road, Piscataway, NJ 08854, USA.
Hyeon-Yeol ChoDepartment of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey, 123 Bevier Road, Piscataway, NJ 08854, USA.
Jeffrey LuoDepartment of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey, 123 Bevier Road, Piscataway, NJ 08854, USA.
Jong-Min LeeDepartment of Mechanical Engineering, Sogang University, 35 Baekbeom-ro, Mapo-gu, Seoul 04107, Republic of Korea.
Sy-Tsong Dean ChuengDepartment of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey, 123 Bevier Road, Piscataway, NJ 08854, USA.
Yannan HouDepartment of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey, 123 Bevier Road, Piscataway, NJ 08854, USA.
Perry To-Tien YinDepartment of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey, 123 Bevier Road, Piscataway, NJ 08854, USA.
Jiyou HanCollege of Life Sciences & Biotechnology, Science Campus, Korea University, 145 Anam-ro, Seongbuk-gu, Seoul 02741, Republic of Korea.
Jong Hoon KimCollege of Life Sciences & Biotechnology, Science Campus, Korea University, 145 Anam-ro, Seongbuk-gu, Seoul 02741, Republic of Korea.
Bong Geun ChungDepartment of Mechanical Engineering, Sogang University, 35 Baekbeom-ro, Mapo-gu, Seoul 04107, Republic of Korea.
Jeong-Woo ChoiDepartment of Chemical & Biomolecular Engineering, Sogang University, 35 Baekbeom-ro, Mapo-gu, Seoul 04107, Republic of Korea.
Ki-Bum LeeDepartment of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey, 123 Bevier Road, Piscataway, NJ 08854, USA.
Rutgers, The State University of New Jersey · USSogang University · KRKorea University · KR

Funding

X-RAY STRUCTURE OF RIFM PROTEIN FROM THE BIOSYNTHESIS PATHWAY OF THE ANSAMYCIN AP41RR012408 · NCRR · BROOKHAVEN SCIENCE ASSOC-BROOKHAVEN LAB · PI MARIUZZA, ROY A · 1998 to 2011
$32.2M
Rutgers Biotechnology Training ProgramT32GM135141 · NIGMS · RUTGERS, THE STATE UNIV OF N.J. · PI ANN M. STOCK, Martin L Yarmush · 2020 to 2026
$3.5M
Machine learning-enabled Comparative Transcriptomic Profiling to Validate NanoScript-induced Inner Ear Hair CellsR01DC016612 · NIDCD · RUTGERS, THE STATE UNIV OF N.J. · PI KWAN, KELVIN Y., LEE, KIBUM · 2018 to 2022
$2.8M
Nanoparticle-based synthetic transcription factor to induce stem cell myogenesisR21AR071101 · NIAMS · RUTGERS, THE STATE UNIV OF N.J. · PI LEE, KIBUM · 2017 to 2018
$371k
NCRR NIH HHS P41 RR012408NIAMS NIH HHS R21 AR071101NIDCD NIH HHS R01 DC016612NIGMS NIH HHS T32 GM135141
6 · The paper itself

Abstract

Nanoparticle-based nucleic acid conjugates (NP-NACs) hold great promise for theragnostic (diagnostic and therapeutic) applications. However, several limitations have hindered the realization of their full potential in the clinical treatment of cancer and other diseases. In diagnosis, NP-NACs, combined with conventional optical sensing systems, have been applied for cancer detection

Indexed as

Graphene hybrid nanomaterialsMultimodal cancer theragnosticsNanomedicineNanoparticle-based nucleic acid conjugatesPersonalized medicine

Identifiers

PMID33776614
PMCPMC7996391
OpenAlexW3093718519

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.