Evidence map›Paper›PMID 33776568›Full record

ArticleJournal of medical biochemistry2021

Assessment of hematologic indices and their correlation to hemoglobin A1c among Bosnian children with type 1 diabetes mellitus and their healthy peers.

Suzana Tihić-Kapidžić, Adlija Čaušević, Jasmina Fočo-Solak, Maja Malenica, Tanja Dujić, Sniježana Hasanbegović, Nermina Babić, Ermin Begović

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In one paragraph

Article in Journal of medical biochemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Suzana Tihić-KapidžićUniversity of Sarajevo, Clinical Centre, Department for Clinical Biochemistry and Immunology, Sarajevo, Bosnia and Herzegovina.
Adlija ČauševićUniversity of Sarajevo, Faculty of Pharmacy, Department of Biochemistry and Clinical Analysis, Sarajevo, Bosnia and Herzegovina.
Jasmina Fočo-SolakUniversity of Sarajevo, Clinical Centre, Department for Clinical Biochemistry and Immunology, Sarajevo, Bosnia and Herzegovina.
Maja MalenicaUniversity of Sarajevo, Faculty of Pharmacy, Department of Biochemistry and Clinical Analysis, Sarajevo, Bosnia and Herzegovina.
Tanja DujićUniversity of Sarajevo, Faculty of Pharmacy, Department of Biochemistry and Clinical Analysis, Sarajevo, Bosnia and Herzegovina.
Sniježana HasanbegovićClinical Centre University of Sarajevo, Pediatric Clinic, Sarajevo, Bosnia and Herzegovina.
Nermina BabićUniversity of Sarajevo, Medical Faculty, Department of Human Physiology, Sarajevo, Bosnia and Herzegovina.
Ermin BegovićUniversity of Sarajevo, Clinical Centre, Department for Clinical Biochemistry and Immunology, Sarajevo, Bosnia and Herzegovina.
University of Sarajevo · BA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAltered levels of many hematological parameters have been directly associated with diabetes in adults, while studies on children with type 1 diabetes mellitus are lacking. The aim of this study was to determine hematological indices in diabetic Bosnian children in comparison to healthy controls as well as to correlate their levels to blood glucose and hemoglobin A1c.

methods100 healthy and 100 children with type 1 diabetes mellitus (age 1-18) were included in this study. Complete blood count, hemoglobin A1c, and glucose were tested. Results were analysed by IBM SPSS Statistics version 23.

resultsSignificant differences (p<0.05) between healthy and diabetic children were found in relation to HbA1c, glucose, mean platelet volume, the number of white blood cells and erythrocytes, hematocrit, hemoglobin and MCH values. No gender differences or significant age differences were seen for hemoglobin, hematocrit, and MCV, while platelets, MPV, and MCH differed by age only in healthy children. When diabetic children were classified according to HbA1c levels, significant differences were seen for erythrocyte count and hematocrit value (p=0.013 and 0.019, respectively). The number of erythrocytes and white blood cells correlated significantly with HbA1c (p=0.037 and 0.027, respectively).

conclusionsLower levels of erythrocytes, hematocrit, and hemoglobin in diabetic compared to healthy children indicate possible development of anemia, while higher MCV, MCH, and MPV values indicate an alteration in erythrocyte morphology. Hematological indices could be a useful inexpensive tool in the diagnosis and follow up of type 1 diabetes in children.

Indexed as

hematological indiceshemoglobin A1cpediatric populationtype 1 diabetes mellitus

Identifiers

PMID33776568
PMCPMC7982283
OpenAlexW3044146593

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.