ReviewCurrent treatment options in cardiovascular medicine2021
New Approaches to Donor Selection and Preparation in Heart Transplantation.
Review in Current treatment options in cardiovascular medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 34 citations in OpenAlex.
- Extended Criteria Donor Use in Heart Transplantation: A Promising Strategy to Expand the Donor Pool.Journal of clinical medicine · 2026Article
- Article
- Reasons for donor heart offer refusal in the United States: Results from 14,132 transplant clinician surveys in the Donor Heart Study.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2025Observational
- Evaluation of target temperature on effectiveness of myocardial preservation during hypothermic machine perfusion.JHLT open · 2025Article
- Improving the Prioritization of Heart Transplantation Candidates for Optimal Clinical Outcomes: A Narrative Review.Current cardiology reports · 2025Review
- Advancements in textile techniques for cardiovascular tissue replacement and repair.APL bioengineering · 2024Review
- Prediction of Donor Heart Acceptance for Transplant and Its Clinical Implications: Results From The Donor Heart Study.Circulation. Heart failure · 2024Review
- Exercise capacity and cardiac allograft ischemic time in recent heart transplant recipients.JHLT open · 2024Article
- Beating Heart Transplant Procedures Using Organs From Donors With Circulatory Death.JAMA network open · 2024Article
- Heart transplantation: advances in expanding the donor pool and xenotransplantation.Nature reviews. Cardiology · 2024Review
- Donor Heart Preservation: Current Knowledge and the New Era of Machine Perfusion.International journal of molecular sciences · 2023Review
- ADONHERS (Aged DONor HEart Rescue by Stress Echo) National Protocol: Recipient's Survival after 10-Year Follow-Up.Journal of clinical medicine · 2023Article
- World's first en bloc heart-lung transplantation using the paragonix lungguard donor preservation system.Journal of cardiothoracic surgery · 2023Article
- Venoarterial Extracorporeal Membrane Oxygenation in Cardiogenic Shock to Ventricular Assist Device or Heart Transplantation - Where Are We?Brazilian journal of cardiovascular surgery · 2023Article
- Review
- Heart Transplant Donor Selection Guidelines: Review and Recommendations.Current cardiology reports · 2022Review
- Trends and Outcomes of Cardiac Transplantation in the Lowest Urgency Candidates.Journal of the American Heart Association · 2021Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purpose of reviewWith increasing survival of patients with stage D heart failure, the demand for heart transplantation has increased. The supply of donor hearts remains relatively limited. Strategies have been investigated and new technologies have been developed to expand the current donor pool. These new approaches will be discussed herein. RECENT
findingsDonor hearts are often considered "marginal" due to risk factors such as older age, size mismatch with the intended recipient, prolonged ischemic time, presence of left ventricular hypertrophy, and hepatitis B/C infection. We reviewed recent data regarding the use of donor hearts with these risk factors and suggest ways to safely liberalize current donor heart acceptance criteria. New technologies such as temperature-controlled transport systems and ex vivo cardiac perfusion methods have also demonstrated promising short-term and intermediate outcomes as compared with routine cold storage, by promoting heart preservation and enabling heart procurement from remote sites with shorter cold ischemic time. Recent use of hearts from donation after circulatory death donors has demonstrated comparable outcomes to conventional donation after brain death, which can further expand the current donor pool. SUMMARY: Careful selection of "marginal" donor hearts, use of ex vivo cardiac perfusion, and acceptance of hearts after circulatory death may expand our current cardiac donor pool with comparable outcomes to conventional donor selection and preparation methods.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.