Evidence map›Paper›PMID 33776297›Full record

ReviewVeterinary world2021

The use of probiotics in animal feeding for safe production and as potential alternatives to antibiotics.

Mbarga M J Arsène, Anyutoulou K L Davares, Smolyakova L Andreevna, Ermolaev A Vladimirovich, Bassa Z Carime, Razan Marouf, Ibrahim Khelifi

Open access · goldAbstract readReview
In one paragraph

Review in Veterinary world, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed
8.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 127 citations in OpenAlex.

  1. Article
  2. Effects ofAnimals : an open access journal from MDPI · 2026
    Article
  3. Article
  4. Review
  5. Probiotic Potential ofFoods (Basel, Switzerland) · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Supplementation effects of feed additive containing eggshell,Journal of animal science and technology · 2025
    Article
  13. Lactic acid bacteria viability and interactions in recirculating aquaculture systems for fish farming.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025
    Article
  14. Review
  15. Article
  16. Review
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Mbarga M J ArsèneDepartment of microbiology and virology, Institute of Medicine, RUDN University, Moscow, Russia.
Anyutoulou K L DavaresDepartment of Food Sciences and Nutrition, National School of Agro-industrial Sciences, University of Ngaoundere, Cameroon.
Smolyakova L AndreevnaDepartment of microbiology and virology, Institute of Medicine, RUDN University, Moscow, Russia.
Ermolaev A VladimirovichDepartment of microbiology and virology, Institute of Medicine, RUDN University, Moscow, Russia.
Bassa Z CarimeDepartment of Food Sciences and Nutrition, National School of Agro-industrial Sciences, University of Ngaoundere, Cameroon.
Razan MaroufDepartment of microbiology and virology, Institute of Medicine, RUDN University, Moscow, Russia.
Ibrahim KhelifiDepartment of microbiology and virology, Institute of Medicine, RUDN University, Moscow, Russia.
Institute of Virology of the Slovak Academy of Sciences · SKUniversity of Ngaoundéré · CM

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although the production of safe food for human consumption is the primary purpose for animal rearing, the environment and well-being of the animals must also be taken into consideration. Based on microbiological point of view, the production of healthy food from animals involves considering foodborne pathogens, on the one hand and on the other hand, the methods used to fight against germs during breeding. The conventional method to control or prevent bacterial infections in farming is the use antibiotics. However, the banning of these compounds as growth promoters caused many changes in animal breeding and their use has since been limited to the treatment and prevention of bacterial infections. In this function, their importance no longer needs to be demonstrated, but unfortunately, their excessive and abusive use have led to a double problem which can have harmful consequences on consumer health: Resistance to antibiotics and the presence of antibiotic residues in food. The use of probiotics appears to be a suitable alternative to overcome these problems because of their ability to modulate the immune system and intestinal microflora, and further considering their antagonistic role against certain pathogenic bacteria and their ability to play the role of growth factor (sometimes associated with prebiotics) when used as feed additives. This review aims to highlight some of the negative effects of the use of antibiotics in animal rearing as well as emphasize the current knowledge on the use of probiotics as a feed additive, their influence on animal production and their potential utility as an alternative to conventional antibiotics, particularly in poultry, pig, and fish farming.

Indexed as

animal nutritionantibiotic resistancefeed additivefish farmingpig poultryprobioticsafe production

Identifiers

PMID33776297
PMCPMC7994123
OpenAlexW3128209128

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.