ArticleHellenike cheirourgike. Acta chirurgica Hellenica2020
Determinants of Mortality in Necrotizing Soft Tissue Infections.
Article in Hellenike cheirourgike. Acta chirurgica Hellenica, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
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Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Vacuum-assisted closure versus conventional dressing in necrotizing fasciitis: a systematic review and meta-analysis.Journal of orthopaedic surgery and research · 2023Pooled it
- Results of surgical treatment of necrotizing soft tissue infections. A 15-years retrospective cohort study of a single center of emergency surgery.Langenbeck's archives of surgery · 2026Article
- A Case Report of Rapidly Necrotizing Fasciitis Post-Falling Down Treated Reconstructively.Cureus · 2022Article
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Authors and funding
5 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundNecrotizing soft tissue infections (NSTI) are frequently encountered, with a high mortality despite advances in health care. MATERIAL AND
methodsPatients presenting with NSTI were prospectively followed up in an attempt to identify factors that were significantly associated with mortality.
resultsThere were a total of 86 patients [65 males (75.6%) and 21 females (24.4%)] with an overall mortality of 33.7% (29 patients). The average age was 50.37 years and trauma was the commonest aetiology (34 patients, 66.7%). The average duration of symptoms prior to presentation was 10.56 days; the lower limb was most commonly involved (62 patients, 72.09%). Fifty nine patients had comorbidities (commonest being diabetes mellitus in 41). Age above 50 years, symptoms for more than 8.5 days, involved surface area more than 15.5%, of the total body surface, on-admission pulse rate more than 99 beats/minute, systolic blood pressure less than 103 mm Hg, Glasgow scale less than 12, need for inotropes, low hemoglobin, high leukocyte counts, uraemia, deranged coagulation, low serum albumin, and high levels of lactic acid were significant for mortality. On multivariate analysis, only age above 50 years, presence of acidosis and low serum albumin significantly affected survival.
conclusionNSTI carry high mortality. The identification of potential risk factors associated with mortality might help in guiding and optimizing the management of patients who present with NSTI.
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