Evidence map›Paper›PMID 33775448›Full record

ArticleDrug and alcohol dependence2021

The influence of social relationships on substance use behaviors among pregnant women with opioid use disorder.

Dena Asta, Alex Davis, Tamar Krishnamurti, Leah Klocke, Walitta Abdullah, Elizabeth E Krans

Open access · greenAbstract read
In one paragraph

Article in Drug and alcohol dependence, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
6.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Dena AstaDepartment of Statistics, The Ohio State University, 1958 Neil Ave, Columbus, OH, 43210, USA; Translational Data Analytics Institute, The Ohio State University, 1760 Neil Ave, Columbus, OH, 43210, USA. Electronic address: dasta@stat.osu.edu.
Alex DavisDepartment of Engineering and Public Policy, Carnegie Mellon University, 5000 Forbes Ave, Baker Hall 129, Pittsburgh, PA, 15213, USA.
Tamar KrishnamurtiDepartment of General Internal Medicine, University of Pittsburgh School of Medicine, 200 Meyran Ave. Suite 200, Pittsburgh, PA, 15213, USA.
Leah KlockeMagee-Womens Research Institute, 204 Craft Ave, Pittsburgh, PA, 15213, USA.
Walitta AbdullahMagee-Womens Research Institute, 204 Craft Ave, Pittsburgh, PA, 15213, USA.
Elizabeth E KransMagee-Womens Research Institute, 204 Craft Ave, Pittsburgh, PA, 15213, USA; Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh School of Medicine, 300 Halket Street, Pittsburgh, PA, 15213, USA.
Magee-Womens Research Institute · USUniversity of Pittsburgh · USCarnegie Mellon University · USThe Ohio State University · US

Funding

Institutional Career Development CoreKL2TR001856 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI RAY, KRISTIN N, RUBIO, DORIS M · 2016 to 2025
$13.8M
NCATS NIH HHS KL2 TR001856
6 · The paper itself

Abstract

objectiveTo describe the social network characteristics of pregnant women with opioid use disorder (OUD) and explore how changes in social relationships during pregnancy may influence substance use behaviors.

methodsBetween 2017 and 2018, we conducted an exploratory pilot study among 50 pregnant women with OUD. Participants completed a detailed social network inventory to describe the behaviors (e.g. substance-using), social support characteristics (e.g. financial, emotional, informational) and roles (e.g. family member, friend) of network members. The primary outcome was a self-reported decrease in substance use during pregnancy. Pearson correlations were used to test for associations between covariates reflecting different aspects of participants' social networks and decreased substance use during pregnancy.

resultsMost participants (84.0 %) decreased substance use during pregnancy and stated that pregnancy motivated them to engage in treatment (94.0 %). Participants had a median of 8 (IQR: 4-18) network members with differing proportions of those who did and did not use substances. Pregnancy prompted participants to significantly increase contact with (26.4 % vs. 5.0 %), have increased support from (35.7 % vs. 7.5 %), and a have a feeling of increased closeness with (26.1 % vs. 3.3 %) network members who did not use substances. However, decreased substance use during pregnancy was most strongly (negatively) associated with the proportion of network members who used substances and provided informational support (r=-0.25, p = 0.08) and a feeling of closeness (r=-0.26, p = 0.08).

conclusionsOur findings indicate that pregnancy has a profound influence on women's substance use behaviors and that changes in social relationships due to pregnancy may influence substance use.

Indexed as

Opioid-Related DisordersPregnant PeopleFemaleHumansInterpersonal RelationsPilot ProjectsPregnancySocial NetworkingSocial SupportOpioid use disorderPregnancySocial networkSocial supportSubstance use disorder

Identifiers

PMID33775448
PMCPMC8627830
OpenAlexW3137323987

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.