Evidence map›Paper›PMID 33775175›Full record

Trial reportPalliative medicine2021

Caregiver-guided pain coping skills training for patients with advanced cancer: Results from a randomized clinical trial.

Laura S Porter, Jennifer L Steel, Diane L Fairclough, Thomas W LeBlanc, Janet Bull, Laura C Hanson, Stacy Fischer, Francis J Keefe

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Palliative medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Trial
  5. Article
  6. Review
  7. Training and Preparedness among Informal Cancer Caregivers.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 1 country.

Laura S PorterDuke University School of Medicine, Durham, NC, USA.ORCID 0000-0002-2962-2378
Jennifer L SteelUniversity of Pittsburgh, Pittsburgh, PA, USA.
Diane L FaircloughColorado School of Public Health, Arora, CO, USA.
Thomas W LeBlancDuke University School of Medicine, Durham, NC, USA.ORCID 0000-0002-0546-7895
Janet BullFour Seasons Compassion for Life, Hendersonville, NC, USA.
Laura C HansonDivision of Geriatric Medicine & Palliative Care Program, University of North Carolina, Chapel Hill, NC, USA.
Stacy FischerUniversity of Colorado, Denver, CO, USA.
Francis J KeefeDuke University School of Medicine, Durham, NC, USA.
Duke University · USColorado School of Public Health · USFour Seasons · USUniversity of Colorado Denver · USUniversity of North Carolina at Chapel Hill · USUniversity of Pittsburgh · US

Funding

Refinement and Expansion of the Palliative Care Research Cooperative Group (PCRC)U24NR014637 · NINR · DUKE UNIVERSITY · PI KUTNER, JEAN S, POLLAK, KATHRYN I · 2013 to 2017
$9.6M
Palliative Care Research Cooperative Group (PCRC): Refinement and ExpansionU2CNR014637 · NINR · UNIVERSITY OF COLORADO DENVER · PI KUTNER, JEAN S, POLLAK, KATHRYN I · 2018 to 2022
$8.6M
Couple Communication in Cancer: A Multi-Method Examination - Renewal - 1R01CA201179 · NCI · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI Shelby Langer, LAURA S PORTER · 2016 to 2026
$7.2M
Caregiver-Guided Pain Management Training in Palliative CareR01NR015348 · NINR · DUKE UNIVERSITY · PI KEEFE, FRANCIS J., PORTER, LAURA S · 2014 to 2017
$2.0M
NCI NIH HHS R01 CA201179NINR NIH HHS R01 NR015348NINR NIH HHS U24 NR014637NINR NIH HHS U2C NR014637
6 · The paper itself

Abstract

backgroundPain is a major concern among patients with advanced cancer and their family caregivers. Evidence suggests that pain coping skills training interventions can improve outcomes, however they have rarely been tested in this population.

aimTo test the efficacy of a caregiver-guided pain coping skills training intervention. The primary outcome was caregiver self-efficacy for helping the patient manage pain.

designA randomized controlled trial compared the intervention to an enhanced treatment-as-usual control. Dyads in both conditions received pain education, and those in the intervention received three sessions of pain coping skills training. Caregiver outcomes (self-efficacy; caregiver strain, caregiving satisfaction, psychological distress) and patient outcomes (self-efficacy, pain intensity and interference, psychological distress) were collected at baseline and post-intervention. SETTING/

participantsTwo hundred two patients with stage III-IV cancer and pain and their family caregivers were enrolled from four outpatient oncology clinics and a free-standing hospice/palliative care organization.

resultsCompared to those in the control arm, caregivers in the intervention reported significant increases in caregiving satisfaction (

conclusionsThis is the first study to test a pain coping skills intervention targeted to patients and caregivers facing advanced cancer. Findings suggest that pain education provides benefits for patients and caregivers, and coping skills training may be beneficial for caregivers. Further research is needed to optimize the benefits of education and pain coping skills training for improving cancer pain outcomes.

Indexed as

CaregiversNeoplasmsAdaptation, PsychologicalHumansPainQuality of Lifebehavioral medicineCancerclinical trialfamily caregiverspain

Identifiers

PMID33775175
PMCPMC8265951
OpenAlexW3140841239

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.