ArticleJournal of the American Heart Association2021
Right Ventricular Pulmonary Artery Coupling and Mortality in Cardiac Intensive Care Unit Patients.
Article in Journal of the American Heart Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06887140 (Prognostic Value of Right Ventricular-pulmonary Arterial Coupling Assessed by Echocardiography in Septic Patients), which is not on this map. Cited by 27 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Prognostic Value of Right Ventricular-pulmonary Arterial Coupling Assessed by Echocardiography in Septic Patients: A Prospective Observational Study
Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Ventriculo-arterial coupling in acute heart failure: prognostic and therapeutic insights - a systematic review and meta-analysis of multivariable-adjusted data.Heart failure reviews · 2026Pooled it
- Pressure-Adjusted Heart Rate by Echocardiography and Mortality in the Cardiac Intensive Care Unit.JACC. Advances · 2026Article
- Comprehensive Understanding and Diagnostic Approaches to Acute Right Ventricular Failure in the CCU.International journal of heart failure · 2026Article
- Right Ventricular Function and Mortality in Critically Ill Patients With Heart Failure and Cardiogenic Shock.International journal of heart failure · 2026Article
- Prognostic value of right ventricular-pulmonary artery coupling in patients with muscular dystrophies.Scientific reports · 2026Article
- Prognostic impact of right ventricular to pulmonary arterial coupling for patients undergoing surgery for severe mitral regurgitation.European heart journal. Imaging methods and practice · 2026Article
- Echocardiographic Predictors of Mortality in Cardiac Intensive Care Unit Patients With Pulmonary Hypertension.The American journal of cardiology · 2025Article
- Pulmonary Effective Arterial Elastance by Echocardiography and Mortality in the Cardiac Intensive Care Unit.JACC. Advances · 2025Article
- Gaps and Knowledge in the Contemporary Management of Acute Right Ventricular Failure.Circulation. Heart failure · 2025Review
- Additive Value of Right Ventricular Global Longitudinal Strain to a Conventional Echocardiographic Parameter to Improve Prognostic Value in Intermediate-Risk Pulmonary Embolism.Journal of the American Heart Association · 2025Article
- Tricuspid annular plane systolic excursion/pulmonary arterial systolic pressure ratio as a predictor of outcome in acute heart failure.La Tunisie medicale · 2025Article
- Prognostic value of the ratio between right ventricular free wall longitudinal strain and systolic pulmonary artery pressure in patients with heart failure with reduced ejection fraction and ventricular secondary mitral regurgitation.Frontiers in cardiovascular medicine · 2025Article
- Phosphodiesterase 9A inhibition improves aging-related increase in pulmonary vascular resistance in mice.GeroScience · 2024Article
- Pulmonary Artery Pressures and Mortality During Venoarterial ECMO: An ELSO Registry Analysis.Circulation. Heart failure · 2024Article
- Application of an echocardiographic index to characterize right ventricular-pulmonary arterial coupling in heart failure.ESC heart failure · 2024Review
- The value of right ventricular to pulmonary arterial coupling in the critically ill: a National Echocardiography Database of Australia (NEDA) substudy.Annals of intensive care · 2024Article
- Current trends and latest developments in echocardiographic assessment of right ventricular function: load dependency perspective.Frontiers in cardiovascular medicine · 2024Review
- Phrenic Nerve Stimulation for Acute Respiratory Failure.Respiratory care · 2023Article
- Enhancing Prognostication in Acute Heart Failure: Significance of RV-PA Coupling and the TAPSE/PASP Ratio.Journal of cardiovascular imaging · 2023Article
- The Role of Right Ventriculo-Arterial Coupling in Symptoms Presentation of Patients with Hypertrophic Cardiomyopathy.Journal of clinical medicine · 2023Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background Impaired right ventricular (RV) pulmonary artery coupling has been associated with higher mortality in patients with chronic heart disease, but few studies have examined this metric in critically ill patients. We sought to evaluate the association between RV pulmonary artery coupling, defined by the ratio of tricuspid annular peak systolic tissue Doppler velocity (TASV)/estimated RV systolic pressure (RVSP), and mortality in cardiac intensive care unit patients. Methods and Results Using a database of unique cardiac intensive care unit admissions from 2007 to 2018, we included patients with TASV/RVSP ratio measured within 1 day of hospitalization. Hospital mortality was analyzed using multivariable logistic regression, and 1-year mortality was analyzed using multivariable Cox proportional-hazards analysis. We included 4259 patients with a mean age of 69±15 years (40.1% women). Admission diagnoses included acute coronary syndrome in 56%, heart failure in 52%, respiratory failure in 24%, and cardiogenic shock in 12%. The mean TASV/RVSP ratio was 0.31±0.14, and in-hospital mortality occurred in 7% of patients. Higher TASV/RVSP ratio was associated with lower in-hospital mortality (adjusted unit odds ratio, 0.68 per each 0.1-unit higher ratio; 95% CI, 0.58-0.79;
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