Evidence map›Paper›PMID 33774931›Full record

ArticleJournal of veterinary science2021

Protective efficacy of attenuated

Mwense Leya, Won Kyong Kim, Enkhsaikhan Ochirkhuyag, Eun Chae Yu, Young Jee Kim, Yoonhwan Yeo, Myeon Sik Yang, Sang Seop Han, John Hwa Lee, Dongseob Tark and 2 more

Open access · goldAbstract readRandomized Controlled Trial, Veterinary
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of veterinary science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Mwense Leya *College of Veterinary Medicine, Jeonbuk National University, Iksan 54596, Korea.ORCID https://orcid.org/0000-0003-2304-4551
Won Kyong Kim *College of Veterinary Medicine, Jeonbuk National University, Iksan 54596, Korea.ORCID https://orcid.org/0000-0003-3015-0416
Enkhsaikhan OchirkhuyagCollege of Veterinary Medicine, Jeonbuk National University, Iksan 54596, Korea.ORCID https://orcid.org/0000-0001-5176-0868
Eun Chae YuKorea Zoonosis Research institute, Jeonbuk National University, Iksan 54531, Korea.ORCID https://orcid.org/0000-0002-2237-0139
Young Jee KimKorea Zoonosis Research institute, Jeonbuk National University, Iksan 54531, Korea.ORCID https://orcid.org/0000-0003-0836-6608
Yoonhwan YeoKorea Zoonosis Research institute, Jeonbuk National University, Iksan 54531, Korea.ORCID https://orcid.org/0000-0002-2018-6063
Myeon Sik YangCollege of Veterinary Medicine, Jeonbuk National University, Iksan 54596, Korea.ORCID https://orcid.org/0000-0003-1858-3729
Sang Seop HanKorea Zoonosis Research institute, Jeonbuk National University, Iksan 54531, Korea.ORCID https://orcid.org/0000-0002-0809-6540
John Hwa LeeCollege of Veterinary Medicine, Jeonbuk National University, Iksan 54596, Korea.ORCID https://orcid.org/0000-0002-2028-2207
Dongseob TarkKorea Zoonosis Research institute, Jeonbuk National University, Iksan 54531, Korea.ORCID https://orcid.org/0000-0001-7499-4253
Jin HurCollege of Veterinary Medicine, Jeonbuk National University, Iksan 54596, Korea.ORCID https://orcid.org/0000-0003-2658-0747
Bumseok KimCollege of Veterinary Medicine, Jeonbuk National University, Iksan 54596, Korea. bskims@jbnu.ac.kr.ORCID https://orcid.org/0000-0003-0392-2513
Jeonbuk National University · KR

Funding

Korea Health Industry Development Institute HI16C2130National Research Foundation of Korea 2019R1A6A1A03033084
6 · The paper itself

Abstract

backgroundAttenuated

objectivesThe study aimed to determine the protective efficacy of attenuated

methodsGoats were vaccinated with

resultsAmong these vaccines inoculated at 5 × 10⁹ CFU/mL in 1 mL, Omp19 or SOD showed significantly higher serum immunoglobulin G titers at (2, 4, and 6) weeks post-vaccination, compared to the vector control. Interferon-γ production in response to individual antigens was significantly higher in SOD, Omp19, PrpA, and BLS individual groups, compared to that in the vector control (all

conclusionsThese results delineated that BLS, Omp19, PrpA, and SOD proteins achieved a definite level of protection, indicating that

Indexed as

Immunity, CellularAnimalsAntigens, BacterialBrucella abortusBrucella VaccineFemaleGoat DiseasesGoatsSalmonella typhimuriumVaccines, SyntheticAntigens, BacterialBrucella VaccineVaccines, SyntheticBrucellosisgoatSalmonellavaccine

Identifiers

PMID33774931
PMCPMC8007450
OpenAlexW3131976481

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.