Evidence map›Paper›PMID 33774801›Full record

SynthesisJournal of neuro-oncology2021

Racial and ethnic disparities among children with primary central nervous system tumors in the US.

Edwin Nieblas-Bedolla, Briana Christophers, John R Williams, Alexandra Power-Hays, Nathalia Jimenez, Analiz Rodriguez

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Journal of neuro-oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Disparities in Neuro-Oncology.Current neurology and neuroscience reports · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Edwin Nieblas-Bedolla *University of Washington School of Medicine, Seattle, WA, USA. ednb@uw.edu.ORCID http://orcid.org/0000-0001-5879-1800
Briana Christophers *Weill Cornell/Rockefeller/Sloan Kettering Tri-Institutional MD-PhD Program, New York, NY, USA.ORCID http://orcid.org/0000-0001-5248-069X
John R WilliamsDepartment of Neurological Surgery, University of Washington, Seattle, WA, USA.
Alexandra Power-HaysCincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.ORCID http://orcid.org/0000-0002-5823-0218
Nathalia JimenezDepartment of Anesthesiology and Pain Medicine, University of Washington, Seattle, WA, USA.ORCID http://orcid.org/0000-0002-6785-8330
Analiz RodriguezDepartment of Neurosurgery, University of Arkansas for Medical Sciences, Little Rock, AR, USA.ORCID http://orcid.org/0000-0003-3426-0508
University of Washington · USCincinnati Children's Hospital Medical Center · USCornell University · USSeattle Children's Hospital · USUniversity of Arkansas for Medical Sciences · US

Funding

Weill Cornell/Rockefeller/Sloan-Kettering MST ProgramT32GM007739 · NIGMS · WEILL MEDICAL COLL OF CORNELL UNIV · PI HSU, KATHARINE C · 1985 to 2023
$51.1M
National Institute of General Medical Sciences (US) T32GM007739
6 · The paper itself

Abstract

introductionPrimary central nervous system (CNS) tumors are among the most common and lethal types of cancer in children. However, the existence of health disparities in CNS tumors by race or ethnicity remains poorly understood. This systematic review sought to determine whether racial and ethnic disparities in incidence, healthcare access, and survival exist among pediatric patients diagnosed with CNS tumors.

methodsA search of MEDLINE, Embase, CINAHL, Web of Science, and Scopus was conducted. Inclusion criteria selected for studies published between January 1, 2005 and July 15, 2020 that focused on pediatric populations in the US, evaluated for potential differences based on racial or ethnic backgrounds, and focused on CNS tumors. A standardized study form was used to collect study information, population of interest, research design, and quality of analysis, sample size, participant demographics, pathology evaluated, and incidence or outcomes observed.

resultsA total of 30 studies were inlcuded. Studies suggest White children may be more likely to be diagnosed with a CNS tumor and Hispanic children to present with advanced-stage disease and have worse outcomes. The degree of influence derived from socioeconomic factors is unclear. This review was limited by few available studies that included race and ethnicity as a variable, the overlap in databases used, and unclear categorization of race and ethnicity.

conclusionsThis review identified notable and at times contradicting variations in racial/ethnic disparities among children with CNS tumors, suggesting that the extent of these disparities remains largely unknown and prompts further research to improve health equity.

Indexed as

Central Nervous System NeoplasmsEthnicityChildHealthcare DisparitiesHealth Services AccessibilityHispanic or LatinoHumansSocioeconomic FactorsCentral nervous systemDisparitiesPediatricsPrimary tumor

Identifiers

PMID33774801
OpenAlexW3141205151

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.