Evidence map›Paper›PMID 33774781›Full record

ArticleEnvironmental science and pollution research international2021

Correlation study of parabens in urine, serum, and seminal plasma of adult men in Beijing, China.

Lijia Yu, Fangda Peng, Dong Yuan, Linyuan Zhang, Ying Guo, Bing Chang, Xiaodong Shi, Chunguang Ding, Xiaowei Liang

Abstract read
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In one paragraph

Article in Environmental science and pollution research international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Evaluation of Parabens and Bisphenol A Concentration Levels in Wild Bat Guano Samples.International journal of environmental research and public health · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Lijia YuNational Center for Occupational Safety and Health, NHC, Beijing, 102308, China.ORCID http://orcid.org/0000-0003-3059-7621
Fangda PengNational Center for Occupational Safety and Health, NHC, Beijing, 102308, China.
Dong YuanDepartment of Male Clinical Research, the Key Laboratory of Male Reproductive Health of National Health Commission of PRC, Human Sperm Bank, Research Institute of National Health Commission, Beijing, 100081, China.
Linyuan ZhangNational Institute for Occupational Health and Poison Control, Chinese Center for Disease Control and Prevention, Beijing, 100050, China.
Ying GuoDepartment of Male Clinical Research, the Key Laboratory of Male Reproductive Health of National Health Commission of PRC, Human Sperm Bank, Research Institute of National Health Commission, Beijing, 100081, China.
Bing ChangNational Institute for Occupational Health and Poison Control, Chinese Center for Disease Control and Prevention, Beijing, 100050, China.
Xiaodong ShiNational Center for Occupational Safety and Health, NHC, Beijing, 102308, China.
Chunguang DingNational Center for Occupational Safety and Health, NHC, Beijing, 102308, China. 13466322180@163.com.
Xiaowei LiangDepartment of Male Clinical Research, the Key Laboratory of Male Reproductive Health of National Health Commission of PRC, Human Sperm Bank, Research Institute of National Health Commission, Beijing, 100081, China. liang66xw@163.com.

Funding

National Natural Science Foundation of China 21907021
6 · The paper itself

Abstract

The adverse effects of parabens raise concerns about their extensive use as preservatives in consumer products, especially in cosmetics. Until now, their distribution and excretion in humans have attracted little attention. Here, we quantified various agents including, for the first time, methyl-; ethyl-; n-propyl-; n-butyl-, and i-butylparaben (MeP, EtP, PrP, n-BuP, i-BuP); methyl- and ethyl-protocatechuate (OH-MeP and OH-EtP); hydroxybenzoic acid (4-HB); and 3,4-dihydroxybenzoic acid (3,4-DHB) in urine, serum, and seminal plasma samples from 50 healthy Chinese men in Beijing, China. Urine paraben concentrations were 1-2 orders of magnitudes higher than those in serum and seminal plasma. MeP and PrP were predominant and correlated with each other in the urine, serum, and seminal plasma. In urine, we observed a significant correlation between MeP and OH-MeP; EtP and OH-EtP; and 4-HB and 3,4-DHB concentrations. All these results provide new information on parabens as biomarkers for the assessment of exposure.

Indexed as

ParabensSemenAdultBeijingChinaCorrelation of DataEnvironmental ExposureHumansMaleParabensCorrelation studyExposureParabensUrine, serum, and seminal plasma

Identifiers

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.