ArticleJournal of neurology2021
Do arachnoid cysts grow? A retrospective volumetric study.
Article in Journal of neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed, 4 citations in OpenAlex.
- Molecular characterization of benign intracranial glioependymal and arachnoid cysts suggest heterogeneous mechanisms of action.Journal of neuropathology and experimental neurology · 2025Article
- Atypical Presentation of Idiopathic Intracranial Hypertension: A Case Series and Literature Review.Asian journal of neurosurgery · 2024Article
- The Efficacy and Tolerability of Electroconvulsive Therapy in Psychiatric Patients with Arachnoid Cysts: A Retrospective Chart Study.Brain sciences · 2022Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveArachnoid cysts (ACs) are frequent incidental findings and may be associated with neuropsychiatric symptoms. Usually growth of the ACs with pressure on adjacent brain tissue is regarded as cause of the symptoms. This study was undertaken to identify if and which ACs grow with time.
methodsWe used a large database of cranial MRIs for a retrospective analysis.
resultsDuring a period of 10 years, we collected 166 ACs of 50 persons, mean observational period was 2.5 years. Among these, only larger cysts at the temporal pole, i.e., Galassi II ACs, grew with a rate of 0.3 ml a year (β = 0.32, SE 0.07, p = 0.003); all other ACs remained constant in size or became smaller. All cysts were clinically silent.
conclusionsMost ACs remain constant in size or become smaller. CLASSIFICATION OF EVIDENCE: This study provides Class III evidence that the majority of arachnoid cysts does not grow.
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Registered trials
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