SynthesisBreast cancer research and treatment2021
The impact of mandatory mammographic breast density notification on supplemental screening practice in the United States: a systematic review.
Synthesis in Breast cancer research and treatment, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Clinical guidelines for the management of mammographic density: a systematic review of breast screening guidelines worldwide.JNCI cancer spectrum · 2024Pooled it
- Trial
- Impact of population based breast density notification: multisite parallel arm randomised controlled trial in BreastScreen.BMJ (Clinical research ed.) · 2025Trial
- Psychosocial outcomes and health service use after notifying women participating in population breast screening when they have dense breasts: a BreastScreen Queensland randomised controlled trial.The Medical journal of Australia · 2023Trial
- Australian Women's Intentions and Psychological Outcomes Related to Breast Density Notification and Information: A Randomized Clinical Trial.JAMA network open · 2022Trial
- Dense Breast Legislation and Supplemental Breast Imaging Among Women Undergoing Mammography.JAMA network open · 2026Article
- Changes in Use, Cost, and Value of Breast Cancer Screening Among Older Women in the US.Journal of general internal medicine · 2026Article
- Psychosocial Impact of Breast Density Notification Through Breast Cancer Screening: A Qualitative Interview Study.Health expectations : an international journal of public participation in health care and health policy · 2026Article
- Article
- Supplemental breast cancer screening after negative mammography in US women with dense breasts.Journal of the National Cancer Institute · 2025Article
- Improving breast ultrasonography education: the impact of AI-based decision support on the performance of non-specialist medical professionals.Ultrasonography (Seoul, Korea) · 2025Article
- Current Concepts in Molecular Breast Imaging.Journal of breast imaging · 2025Review
- Changes to the US Preventive Services Task Force Screening Guidelines and Incidence of Breast Cancer.JAMA network open · 2024Article
- Observational
- Screening mammography frequency following dense breast notification among a predominantly Hispanic/Latina screening cohort.Cancer causes & control : CCC · 2024Article
- A Survey of Patient Experience During Molecular Breast Imaging.Journal of nuclear medicine technology · 2024Article
- Using the Translational Science Benefits Model to assess the impact of the Penn Implementation Science Center in Cancer Control.Journal of clinical and translational science · 2024Article
- Protocol for a pragmatic stepped wedge cluster randomized clinical trial testing behavioral economic implementation strategies to increase supplemental breast MRI screening among patients with extremely dense breasts.Implementation science : IS · 2023Article
- Impact of BMI on Prevalence of Dense Breasts by Race and Ethnicity.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2023Article
- A Modified LeNet CNN for Breast Cancer Diagnosis in Ultrasound Images.Diagnostics (Basel, Switzerland) · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
purposeDense breast tissue is an independent risk factor for breast cancer and lowers the sensitivity of screening mammography. Supplemental screening with ultrasound or MRI improves breast cancer detection rate but has potential harms. Breast density notification (BDN) legislation has been introduced in the United States (US) and its impact on supplemental screening practice is unclear. This study systematically reviewed current evidence to explore the impact of BDN on supplemental screening practice in the US.
methodsMedline, PubMed, Embase, Cochrane and the Cinhal Library databases were searched (2009-August 2020). Studies were assessed for eligibility, data were extracted and summarised, and study quality was evaluated.
resultsEvidence from the included studies (n = 14) predominantly showed that BDN legislation increased the overall utilisation of supplemental screening by 0.5-143%. This effect was amplified if the notification included a follow-up telephone call informing women about additional screening benefits, and if the state's law mandated insurance cover for supplemental screening. Likelihood of supplemental screening was also influenced by history of breast biopsy and family history of breast cancer, race, age, socioeconomic status, density category, and physician's specialty and region. Some studies reported increases in biopsy rate (up to 4%) and cancer detection rate (up to 11%) after implementation of BDN legislation.
conclusionBDN leads to increased use of supplemental screening. This has implications for women and the health system. These findings can help inform current and future screening programs, where breast density notification is currently implemented or being considered.
Indexed as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.