Evidence map›Paper›PMID 33774715›Full record

ArticleClinical oral investigations2021

Effects of charcoal-based whitening toothpastes on human enamel in terms of color, surface roughness, and microhardness: an in vitro study.

Uzay Koc Vural, Zeynep Bagdatli, Ayfer Ezgi Yilmaz, Filiz Yalçın Çakır, Emre Altundaşar, Sevil Gurgan

Abstract read
PubMed Publisher
In one paragraph

Article in Clinical oral investigations, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 1 pooled it
11.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 1 synthesis or guideline pooled it, 102 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Effects of Overnight Whitening Pens on Hydrogen Peroxide Penetration, Color Change, and Enamel Surface Properties.Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.] · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Which Whitening Mouthwash With Different Ingredients Is More Effective on Color and Bond Strength of Enamel?Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.] · 2025
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Uzay Koc VuralDepartment of Restorative Dentistry, School of Dentistry, Hacettepe University, 06100 Sıhhıye, Ankara, Turkey. uzaykoc@gmail.com.ORCID http://orcid.org/0000-0002-8764-2174
Zeynep BagdatliDepartment of Restorative Dentistry, School of Dentistry, Hacettepe University, 06100 Sıhhıye, Ankara, Turkey.
Ayfer Ezgi YilmazDepartment of Statistics, Hacettepe University, 06800, Beytepe, Ankara, Turkey.
Filiz Yalçın ÇakırDepartment of Restorative Dentistry, School of Dentistry, Hacettepe University, 06100 Sıhhıye, Ankara, Turkey.
Emre AltundaşarDepartment of Endodontics, Hacettepe University, 06100 Sıhhıye, Ankara, Turkey.
Sevil GurganDepartment of Restorative Dentistry, School of Dentistry, Hacettepe University, 06100 Sıhhıye, Ankara, Turkey.
Hacettepe University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveCharcoal based oral care products have gained popularity in the last few years. The aim of this in vitro study was to compare the effects of different charcoal based whitening toothpastes on color, surface roughness and microhardness of human enamel. MATERIALS AND

methodsForty-eight specimens obtained from human permanent upper incisor teeth were randomly divided into 4 groups(n=12):Group-1:Colgate Total 12(CT); Group-2:Body Kingdom(BK); Group-3:Black is White(BW), Group-4:Colgate optic white(COW). Following 4 days cycle of darkening(2-min chlorhexidine and 60-min black tea per day), a 12- week brushing(twice daily for 1 min)was performed. Color of specimens was measured using a spectrophotometer. A contact type profilometer was used to measure surface roughness (Ra) and Vicker's hardness tester was used for the changes in microhardness(VHN). A representative sample from each group was visualized by SEM. Data were analyzed by One-way ANOVA, Welch, Fisher's, Kruskall-Wallis, Wilcoxon Sign Rank and Paired t-tests(p<0.05).

resultsAfter 12- week brushing, no differences were found among the groups in terms of color change(p=0.989). All toothpastes tested showed no clinically acceptable whitening performances. A substantial increase in surface roughness was found in all groups, except BW(p<0.05). An increase was found in microhardness with CT(p=0.013), while no changes were found with BK, BW and COW(p>0.05).Only few scratches were observed on the enamel surfaces by SEM evaluations.

conclusionTwelve week brushing with charcoal based whitening toothpastes and a regular fluoridated toothpaste presented similar effects in color of enamel. Surface roughness was increased(except BW) while microhardness was not affected(except CT) with charcoal based whitening toothpastes. CLINICAL RELEVANCE: Charcoal based whitening toothpastes do not promise to whiten the human permanent teeth and their effects on enamel abrasion should not be disregarded.

Indexed as

Dental EnamelTooth BleachingToothpastesCharcoalHumansIncisorToothbrushingCharcoalToothpastesCharcoalCharcoal toothpasteTooth whiteningWhitening toothpaste

Identifiers

PMID33774715
OpenAlexW3144045359

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.