Evidence map›Paper›PMID 33774164›Full record

ArticleJournal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus2021

Ophthalmia neonatorum as the presenting sign of SARS-CoV-2.

Elzbieta Mechel, Minh Trinh, Sylvia Kodsi, Maggie Hymowitz, Mundeep K Kainth, Alice M Lee

Abstract readCase Reports
In one paragraph

Article in Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Elzbieta MechelDepartment of Ophthalmology, Northwell Health, Great Neck, New York.
Minh TrinhDepartment of Ophthalmology, Northwell Health, Great Neck, New York.
Sylvia KodsiDepartment of Ophthalmology, Northwell Health, Great Neck, New York; Department of Pediatrics, Cohen Children's Medical Center, Northwell Health, Queens, New York; Donald and Barbara Zucker School of Medicine at Hofstra, Northwell Health, Hempstead, New York. Electronic address: sylviakodsi@gmail.com.
Maggie HymowitzDepartment of Ophthalmology, Northwell Health, Great Neck, New York; Donald and Barbara Zucker School of Medicine at Hofstra, Northwell Health, Hempstead, New York.
Mundeep K KainthDepartment of Pediatrics, Cohen Children's Medical Center, Northwell Health, Queens, New York; Donald and Barbara Zucker School of Medicine at Hofstra, Northwell Health, Hempstead, New York; Institute of Molecular Medicine, Feinstein Institute for Medical Research, Northwell Health, Manhasset, New York.
Alice M LeeDepartment of Pediatrics, Cohen Children's Medical Center, Northwell Health, Queens, New York; Donald and Barbara Zucker School of Medicine at Hofstra, Northwell Health, Hempstead, New York.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The most common ocular manifestation of SARS-CoV-2 in adults and children is acute conjunctivitis. We report the case of a 4-day-old infant who presented with acute-onset mucopurulent discharge of the left eye as well as subconjunctival hemorrhage and palpebral injection, without corneal findings. A diagnosis of ophthalmia neonatorum was established, for which ocular cultures and Gram staining were performed. No bacterial growth was noted, and polymerase chain reaction (PCR) testing for Chlamydia trachomatis, Neisseria gonorrhea, and herpes simplex were negative. Nasopharyngeal and conjunctival SARS-CoV-2 PCR were positive. Given the identification of SARS-CoV-2 illness, lack of other underlying bacterial or viral etiology on testing, and the well-documented ability for SARS-CoV-2 to cause conjunctivitis, the clinical picture was supportive of ophthalmia neonatorum secondary to SARS-CoV-2. The infant was treated with ceftriaxone and azithromycin prior to culture results. During admission, no systemic findings of Covid-19 illness were observed.

Indexed as

ConjunctivitisCOVID-19GonorrheaOphthalmia NeonatorumAdultChildConjunctivaHumansInfantInfant, NewbornSARS-CoV-2

Identifiers

PMID33774164
PMCPMC7989099

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.