ArticleBMC nephrology2021
Fatigue characteristics on dialysis and non-dialysis days in patients with chronic kidney failure on maintenance hemodialysis.
Article in BMC nephrology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Interventions for fatigue in people with kidney failure requiring dialysis.The Cochrane database of systematic reviews · 2023Pooled it
- Cluster analysis-based classification of fatigue in stable maintenance hemodialysis patients: a prospective cohort study.Journal of nephrology · 2024Trial
- Post-Dialysis Syndrome: A Narrative Review.Kidney360 · 2026Review
- Risk Factors for Fatigue in Adults Receiving Maintenance Hemodialysis Who Have Chronic Pain: A Secondary Analysis of the HOPE Consortium Trial.Kidney medicine · 2026Article
- Investigation of Hemodialysis Patients' Views on Thirst: A Mixed-Methods Study.Healthcare (Basel, Switzerland) · 2025Article
- Interaction between anxiety, depression, and low resilience predicts poor prognosis in patients with chronic kidney disease.World journal of psychiatry · 2025Article
- Lived Experiences of Patients Undergoing Hemodialysis in Selected Teaching Hospitals in Rwanda.Rwanda journal of medicine and health sciences · 2025Article
- Distressing symptoms and health-related quality of life in patients with chronic kidney disease.World journal of nephrology · 2025Article
- Using Ecological Momentary Assessment to Redefine Postdialysis Fatigue in Patients with Kidney Failure.Journal of the American Society of Nephrology : JASN · 2025Article
- Low muscle strength and self-reported fatigue in patients on hemodialysis: findings from the SARC-HD study.Frontiers in nutrition · 2025Article
- Factors affecting postdialysis fatigue among hemodialysis patients: a multi-group path analysis according to nutritional status.Frontiers in medicine · 2025Article
- Factors influencing fatigue among patients undergoing hemodialysis: a multi-center cross-sectional study.The Libyan journal of medicine · 2024Article
- Analysis of factors influencing the trajectory of fatigue in maintenance haemodialysis patients: a longitudinal study.International urology and nephrology · 2024Article
- [Fatigue in chronic physical diseases].Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz · 2024Review
- Article
- Obesogenic Medication Use in End-Stage Kidney Disease and Association With Transplant Listing.Clinical transplantation · 2024Article
- Comparing the effect of warmwater footbath with effleurage and petrissage massages on fatigue of patients undergoing hemodialysis.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2024Article
- Fatigue in Patients Receiving Maintenance Hemodialysis: A Review.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2023Review
- How is exercise being prescribed for patients on hemodialysis? A scoping review.Journal of nephrology · 2023Article
- Association between corrected serum calcium levels after dialysis and post-dialysis fatigue risk: a hospital-based case-control study.European journal of medical research · 2023Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFatigue is prevalent in hemodialysis patients who for survival follow a strict dialysis treatment regimen - dialysis and non-dialysis days. As a result, the daily activities, symptom burden, and clinical outcomes of hemodialysis patients vary significantly between dialysis and non-dialysis days. Fatigue is one of the most reported debilitating symptoms by hemodialysis patients with profound negative impact on their quality of life. Prior studies assessed fatigue during the preceding 7 or 30 days and did not discriminate fatigue characteristics between dialysis and non-dialysis days. We aimed to characterize and compare fatigue severity and fatigue interference with daily activities between dialysis and non-dialysis days.
methodsHemodialysis patients self-reported fatigue on consecutive dialysis and non-dialysis days using the 9-item Brief Fatigue Inventory. The differences in fatigue characteristics between dialysis and non-dialysis days were analyzed using one-way ANCOVA.
resultsGlobal fatigue burden was worse on a dialysis day compared to a non-dialysis day (P for all < 0.001). Age and education were associated with fatigue, but hemodialysis-related variables were not. A significant inverse association of physical activity with fatigue severity observed on non-dialysis day; there was also a negative association between the normalized protein catabolic rate and fatigue severity on both dialysis and non-dialysis days. The positive association of depression with fatigue severity and fatigue interference were consistent on both dialysis and non-dialysis days. None of these factors, however, explained differences in fatigue characteristics between dialysis and non-dialysis days.
conclusionsFatigue, measured in severity and interference, was more pronounced on a dialysis day relative to a non-dialysis day. These differences were not explained by age, sex, education, hemodialysis-related variables, habitual exercise, nutritional status, and or depression. The quantitative measures of fatigue characteristics may facilitate future interventional trials design and better fatigue management for hemodialysis patients.
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