Evidence map›Paper›PMID 33773588›Full record

ArticleAnnals of clinical microbiology and antimicrobials2021

Low sensitivity of conventional fungal agars in fungemia by Rhodotorula mucilaginosa: description of two cases.

Carmen Alicia Garcia-Gutiérrez, María Soledad Cuétara-García, María Dolores Moragues, Jorge Ligero, Sara María Quevedo, María José Buitrago

Open access · goldAbstract readCase Reports
In one paragraph

Article in Annals of clinical microbiology and antimicrobials, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.1field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Animals : an open access journal from MDPI · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Carmen Alicia Garcia-GutiérrezDepartment of Microbiology, Hospital Universitario Severo Ochoa, Leganés, Madrid, Spain.
María Soledad Cuétara-GarcíaDepartment of Microbiology, Hospital Universitario Severo Ochoa, Leganés, Madrid, Spain.
María Dolores MoraguesDepartment of Nursing, School of Medicine and Nursing, University of the Basque Country UPV/EHU, Bilbao, Spain.
Jorge LigeroDepartment of Microbiology, Hospital Universitario Severo Ochoa, Leganés, Madrid, Spain.
Sara María QuevedoDepartment of Microbiology, Hospital Universitario Severo Ochoa, Leganés, Madrid, Spain.
María José BuitragoMycology Reference Laboratory, Centro Nacional de Microbiología, Instituto de Salud Carlos III, Ctra Majadahonda-Pozuelo Km2, 28220, Majadahonda, Madrid, Spain. buitrago@isciii.es.
Hospital Universitario Severo Ochoa · ESInstituto de Salud Carlos III · ESUniversity of the Basque Country · ES

Funding

Consejeria de Educación Universidades e investigación gobierno vasco' IT913-16Instituto de Salud Carlos III PI17CIII/00033
6 · The paper itself

Abstract

backgroundAlthough most bloodstream yeast infections are caused by Candida spp., infections by rare or less common species have increased in recent years. Diagnosis of infections caused by these species is difficult due to the lack of specific symptoms and adequate diagnostic tools. CASES PRESENTATION: We describe two cases of fungemia by Rhodotorula mucilaginosa within a few months of each other, in a secondary Spanish hospital. In both cases, diagnosis was challenging. Blood subcultures in conventional fungal media were persistently negatives and the use of non-conventional fungal media was essential for isolating the yeasts and achieving a correct diagnosis. 1-3 beta-D-glucan detection and a panfungal PCR assay were helpful techniques to confirm the diagnosis

conclusionIt is highly important to establish an early diagnosis for fungemia. The process is challenging because often non-specific symptoms are presents. When yeasts grow in blood cultures other genera than Candida spp. could be the cause of infection. Patient risk factors should be assessed to incorporate alternative culture media and the available rapid diagnostic test, in order to provide an early recognition of the pathogen.

Indexed as

Aged, 80 and overAntifungal AgentsAntigens, FungalBlood CultureCulture MediaFungemiaFungiHumansMaleMicrobiological TechniquesMiddle AgedMycosesRhodotorulaRisk FactorsAntifungal AgentsAntigens, FungalCulture MediaFungemiaRhodotorula mucilaginosaRisk factorsSpecific culture media

Identifiers

PMID33773588
PMCPMC8005224
OpenAlexW3149070304

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.