Evidence map›Paper›PMID 33773081›Full record

ArticleJournal of medical imaging and radiation oncology2021

An MRI framework for respiratory motion modelling validation.

Giorgia Meschini, Chiara Paganelli, Alessandro Vai, Giulia Fontana, Silvia Molinelli, Andrea Pella, Viviana Vitolo, Amelia Barcellini, Ester Orlandi, Mario Ciocca and 2 more

Abstract read
In one paragraph

Article in Journal of medical imaging and radiation oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Giorgia MeschiniDepartment of Electronics, Information and Bioengineering, Politecnico di Milano, Milan, Italy.ORCID https://orcid.org/0000-0001-8759-4291
Chiara PaganelliDepartment of Electronics, Information and Bioengineering, Politecnico di Milano, Milan, Italy.ORCID https://orcid.org/0000-0003-4787-8649
Alessandro VaiNational Centre for Oncological Hadrontherapy (CNAO), Pavia, Italy.
Giulia FontanaNational Centre for Oncological Hadrontherapy (CNAO), Pavia, Italy.
Silvia MolinelliNational Centre for Oncological Hadrontherapy (CNAO), Pavia, Italy.
Andrea PellaNational Centre for Oncological Hadrontherapy (CNAO), Pavia, Italy.
Viviana VitoloNational Centre for Oncological Hadrontherapy (CNAO), Pavia, Italy.
Amelia BarcelliniNational Centre for Oncological Hadrontherapy (CNAO), Pavia, Italy.ORCID https://orcid.org/0000-0002-1595-104X
Ester OrlandiNational Centre for Oncological Hadrontherapy (CNAO), Pavia, Italy.
Mario CioccaNational Centre for Oncological Hadrontherapy (CNAO), Pavia, Italy.
Marco RiboldiDepartment of Medical Physics, Ludwig-Maximilians-Universität (LMU), Garching bei München, Germany.
Guido BaroniDepartment of Electronics, Information and Bioengineering, Politecnico di Milano, Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionRespiratory motion models establish a correspondence between respiratory-correlated (RC) 4-dimensional (4D) imaging and respiratory surrogates, to estimate time-resolved (TR) 3D breathing motion. To evaluate the performance of motion models on real patient data, a validation framework based on magnetic resonance imaging (MRI) is proposed, entailing the use of RC 4DMRI to build the model, and on both (i) TR 2D cine-MRI and (ii) additional 4DMRI data for testing intra-/inter-fraction breathing motion variability.

methodsRepeated MRI data were acquired in 7 patients with abdominal lesions. The considered model relied on deformable image registration (DIR) for building the model and compensating for inter-fraction baseline variations. Both 2D and 3D validation were performed, by comparing model estimations with the ground truth 2D cine-MRI and 4DMRI respiratory phases, respectively.

resultsThe median DIR error was comparable to the voxel size (1.33 × 1.33 × 5 mm

conclusionsResults suggest the potential of the proposed framework in evaluating global motion models for organ motion management in MRI-guided radiotherapy.

Indexed as

Magnetic Resonance ImagingRadiotherapy, Image-GuidedHumansMotionMovementPhantoms, ImagingRespiration4DMRIbreathing motionMRI-guidanceradiation oncology imagingrespiratory motion modelling

Identifiers

PMID33773081
PMCPMC8251859

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.