Evidence map›Paper›PMID 33772705›Full record

ArticleCancer causes & control : CCC2021

Gut microbiome, body weight, and mammographic breast density in healthy postmenopausal women.

Lusine Yaghjyan, Volker Mai, Xuefeng Wang, Maria Ukhanova, Maximiliano Tagliamonte, Yessica C Martinez, Shannan N Rich, Kathleen M Egan

Abstract read
PubMed Publisher
In one paragraph

Article in Cancer causes & control : CCC, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Fecal sample biobanking for breast cancer research focused on the gut microbiome.medRxiv : the preprint server for health sciences · 2025
    Article
  3. Article
  4. Article
  5. Observational
  6. Article
  7. Dietary Patterns and Associated Microbiome Changes that Promote Oncogenesis.Frontiers in cell and developmental biology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Lusine YaghjyanDepartment of Epidemiology, College of Public Health and Health Professions and College of Medicine, University of Florida, Gainesville, FL, USA.
Volker MaiDepartment of Epidemiology, College of Public Health and Health Professions and College of Medicine, University of Florida, Gainesville, FL, USA.
Xuefeng WangH. Lee Moffitt Cancer Center, Tampa, FL, USA.
Maria UkhanovaEmerging Pathogens Institute, University of Florida, Gainesville, FL, USA.
Maximiliano TagliamonteEmerging Pathogens Institute, University of Florida, Gainesville, FL, USA.
Yessica C MartinezH. Lee Moffitt Cancer Center, Tampa, FL, USA.
Shannan N RichDepartment of Epidemiology, College of Public Health and Health Professions and College of Medicine, University of Florida, Gainesville, FL, USA.
Kathleen M EganH. Lee Moffitt Cancer Center, Tampa, FL, USA. Kathleen.Egan@moffitt.org.ORCID http://orcid.org/0000-0001-8772-6979
University of Florida · USMoffitt Cancer Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe examined gut microbiome (GM) profiles in relation to mammographic breast density (BD) and body mass index (BMI) in healthy postmenopausal women.

methodsEligible women were postmenopausal, had a BMI ≤ 35 kg/m

resultsAmong 69 women with BD data, 39 had low BD (BI-RADS I/II) and 30 had high BD (BI-RADS III/IV). BMI was inversely associated with BD (mean BMI = 23.8 and 28.0 in women with high and low BD, respectively, p = 1.07 × 10

conclusionSuggestive differences observed in women with high and low BD with respect to GM alpha diversity and prevalence of specific GM taxa need to be confirmed in larger studies.

Indexed as

Body WeightMicrobiotaAgedBody Mass IndexBreast DensityFecesFemaleGastrointestinal MicrobiomeHumansMiddle AgedPostmenopauseRNA, Ribosomal, 16SRNA, Ribosomal, 16SBreast cancer riskBreast densityIntestinal microbiome

Identifiers

PMID33772705
OpenAlexW3146884365

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.