SynthesisEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2021
Sagittal balance of the cervical spine: a systematic review and meta-analysis.
Synthesis in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05374850 (Impact of Cervical Sagittal Parameters on Interlaminar Epidural Steroid Injection Treatment Outcomes in Patients With Cervical Disc Herniation), which is not on this map. Cited by 25 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Impact of Cervical Sagittal Parameters on Interlaminar Epidural Steroid Injection Treatment Outcomes in Patients With Cervical Disc Herniation
Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Spinopelvic measurements of sagittal balance with deep learning: systematic review and critical evaluation.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2022Pooled it
- Differential Impact of C2-7 Sagittal Vertical Axis on Postoperative Axial Symptoms in Laminoplasty vs Laminectomy With Fusion: A Propensity Score-Trimmed Retrospective Cohort Study.Medical science monitor : international medical journal of experimental and clinical research · 2026Article
- Optimal elevation distance of the X-ray focus in vertical dual-exposure panoramic radiography for mitigating ghost images of cervical vertebrae in the upper incisor region.Oral radiology · 2026Article
- Radiographic Clarity of the External Auditory Meatus as a Cranial Reference Point in Spinal Deformity Patients: A Pilot Interobserver Study.Journal of clinical medicine · 2026Article
- Odontoid Parameters in Adolescent Idiopathic Scoliosis Patients.Clinical spine surgery · 2026Article
- Risk Factors for Radiologic Subaxial Cervical Pathology After C1-2 Posterior Fusion.Journal of clinical medicine · 2026Article
- Review
- Age-associated differences in cervical sagittal alignment parameters among asymptomatic adults: a cross-sectional reference study.Frontiers in neuroscience · 2026Article
- A step-by-step guide for systematic reviews and meta-analyses in spine surgery-study execution: a narrative review.Journal of spine surgery (Hong Kong) · 2025Review
- The effect of cervical parameters on interlaminar epidural steroid injection treatment outcomes in patients with cervical disc herniation.Turkish journal of physical medicine and rehabilitation · 2025Article
- Choosing the right treatment for degenerative cervical myelopathy.Journal of clinical orthopaedics and trauma · 2025Article
- A retrospective cohort analysis of alignment parameters for spinal tumor patients with instrumentation at the cervicothoracic junction.North American Spine Society journal · 2024Article
- Comparative Analysis of Postoperative Sagittal Balance in Expansive Open-Door Laminoplasty versus Laminectomy with Fusion for Multilevel Ossification of Posterior Longitudinal Ligament: A Retrospective Study.Medical science monitor : international medical journal of experimental and clinical research · 2024Article
- C4 constant vertebra: a novel benchmark of physiological cervical sagittal alignment.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2024Article
- Artificial intelligence automatic measurement technology of lumbosacral radiographic parameters.Frontiers in bioengineering and biotechnology · 2024Article
- Sagittal balance parameters measurement on cervical spine MR images based on superpixel segmentation.Frontiers in bioengineering and biotechnology · 2024Article
- A novel classification that defines the normal cervical spine: an analysis based on 632 asymptomatic Chinese volunteers.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2024Article
- Overloaded vertebral body: a unique radiographic phenomenon following multilevel anterior cervical discectomy and fusion.Journal of orthopaedic surgery and research · 2023Article
- Emerging Technologies within Spine Surgery.Life (Basel, Switzerland) · 2023Review
- Age-related changes in cervical sagittal alignment: based on 625 Chinese asymptomatic subjects.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2023Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe purpose of this systematic review and meta-analysis was to compare the cervical sagittal parameters between patients with cervical spine disorder and asymptomatic controls.
methodsTwo independent authors systematically searched online databases including Pubmed, Scopus, Cochrane library, and Web of Science up to June 2020. Cervical sagittal balance parameters, such as T1 slope, cervical SVA (cSVA), and spine cranial angle (SCA), were compared between the cervical spine in healthy, symptomatic, and pre-operative participants. Where possible, we pooled data using random-effects meta-analysis, by CMA software. Heterogeneity and publication bias were assessed using the I-squared statistic and funnel plots, respectively.
resultsA total of 102 studies, comprising 13,802 cases (52.7% female), were included in this meta-analysis. We used the Newcastle-Ottawa Scale (NOS) to evaluate the quality of studies included in this review. Funnel plot and Begg's test did not indicate obvious publication bias. The pooled analysis reveals that the mean (SD) values were: T1 slope (degree), 24.5 (0.98), 25.7 (0.99), 25.4 (0.34); cSVA (mm), 18.7 (1.76), 22.7 (0.66), 22.4 (0.68) for healthy population, symptomatic, and pre-operative assessment, respectively. The mean value of the SCA (degree) was 79.5 (3.55) and 75.6 (10.3) for healthy and symptomatic groups, respectively. Statistical differences were observed between the groups (all P values < 0.001).
conclusionThe findings showed that the T1 slope and the cSVA were significantly lower among patients with cervical spine disorder compared to controls and higher for the SCA. Further well-conducted studies are needed to complement our findings.
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