Evidence map›Paper›PMID 33772513›Full record

ReviewEpileptic disorders : international epilepsy journal with videotape2021

The precuneal cortex: anatomy and seizure semiology.

Ruba R Al-Ramadhani, Veeresh Kumar N Shivamurthy, Kathryn Elkins, Satyanarayana Gedela, Nigel P Pedersen, Ammar Kheder

Open access · greenAbstract readReview
In one paragraph

Review in Epileptic disorders : international epilepsy journal with videotape, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Hidden inside the sulci: Utility of voxel-based morphometric analysis program in localizing precuneus epilepsy.Epileptic disorders : international epilepsy journal with videotape · 2025
    Article
  5. Article
  6. Article
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  11. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Ruba R Al-RamadhaniDepartment of Neurology, Emory University School of Medicine, 201 Dowman Drive, Atlanta, GA 30322, USA.
Veeresh Kumar N ShivamurthyDepartment of Neurology, Emory University School of Medicine, 201 Dowman Drive, Atlanta, GA 30322, USA.
Kathryn ElkinsDepartment of Neurology, Emory University School of Medicine, 201 Dowman Drive, Atlanta, GA 30322, USA.
Satyanarayana GedelaChildren's Healthcare of Atlanta, Atlanta, GA 30322, USA.
Nigel P PedersenDepartment of Neurology, Emory University School of Medicine, 201 Dowman Drive, Atlanta, GA 30322, USA, Emory Epilepsy Center, 12 Executive Park Drive, Atlanta, GA 30329, USA.
Ammar KhederDepartment of Neurology, Emory University School of Medicine, 201 Dowman Drive, Atlanta, GA 30322, USA, Children's Healthcare of Atlanta, Atlanta, GA 30322, USA, Emory Epilepsy Center, 12 Executive Park Drive, Atlanta, GA 30329, USA.
Emory University · USChildren's Healthcare of Atlanta · USEmory and Henry College · US

Funding

Control of the Hippocampal Formation by the Supramammillary Hypothalamus - Anatomy, Physiology and in a Model of Medial Temporal Lobe EpilepsyK08NS105929 · NINDS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI PEDERSEN, NIGEL PAUL · 2018 to 2023
$963k
NINDS NIH HHS K08 NS105929
6 · The paper itself

Abstract

The purpose of this review is to describe the functional anatomy of the precuneal cortex and outline some semiological features of precuneal seizures. The precuneal cortex is a structure that occupies the posterior medial portion of the parietal lobe, and it has broad cortical and subcortical connections. Neuroanatomical tracing, functional imaging, as well as electrical stimulation studies of humans and other primates have elucidated many complex integrative functions of the precuneus including visuo-spatial imagery, sensorimotor functions, and consciousness. Based on the understanding of its functions and connectivity, descriptions of potential seizure semiologies are hypothesized and compared to what is available in the literature. The latter is mostly in the form of case reports or case series. Seizures may involve simple or complex motor or sensory manifestations including abnormal eye movements, visual hallucinations, sensation of motion, or medial temporal-like seizures.

Indexed as

ElectroencephalographySeizuresAnimalsHallucinationsHumansParietal Lobeepilepsy surgeryfocal epilepsiesparietal lobeparietal lobe epilepsyprecuneusSEEG

Identifiers

PMID33772513
PMCPMC8525033
OpenAlexW3138431769

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.