Evidence map›Paper›PMID 33772433›Full record

Trial reportIndian journal of pediatrics2021

Nebulized Magnesium Sulphate in Bronchiolitis: A Randomized Controlled Trial.

Roma Debbarma, Daisy Khera, Surjit Singh, Nisha Toteja, Bharat Choudhary, Kuldeep Singh

Open access · bronzeAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Indian journal of pediatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Roma DebbarmaDepartment of Pediatrics, All India Institute of Medical Sciences, Jodhpur, Rajathan, India.
Daisy KheraDepartment of Pediatrics, All India Institute of Medical Sciences, Jodhpur, Rajathan, India. daisykhera78@gmail.com.ORCID http://orcid.org/0000-0002-2963-1370
Surjit SinghDepartment of Pharmacology, All India Institute of Medical Sciences, Jodhpur, Rajathan, India.
Nisha TotejaDepartment of Pediatrics, All India Institute of Medical Sciences, Gorakhpur, Uttar Pradesh, India.
Bharat ChoudharyDepartment of Trauma & Emergency (Pediatrics), All India Institute of Medical Sciences, Jodhpur, Rajathan, India.
Kuldeep SinghDepartment of Pediatrics, All India Institute of Medical Sciences, Jodhpur, Rajathan, India.
All India Institute of Medical Sciences Jodhpur · INAll India Institute of Medical Sciences · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the efficacy and safety of nebulized magnesium sulphate as a bronchodilator in young children aged 1-24 mo with moderate to severe bronchiolitis in comparison to standard therapy.

methodsThis was an open labeled randomized controlled trial comprising 60 children with moderate to severe bronchiolitis which was randomly assigned to 2 groups. Intervention group received nebulization with 3 mL of 3.2% magnesium sulphate (MgSO

resultsThe mean age of children allocated in the control group was 7.4 ± 5.1 mo and 7.7 ± 4.5 mo in the intervention group. There was no significant difference with respect to improvement of BSS or reduced length of hospitalization in both the groups (p > 0.05). BSS monitored sequentially after enrollment at 1, 2, 4, 8, 12, 16, and 24 h did not show statistically significant differences between the groups. Mean length of hospital stay was 2.89 ± 2.25 d in treatment group and 2.96 ± 1.86 d in control group (p = 0.902). No adverse events were observed in both the groups.

conclusionNebulized magnesium sulphate is not superior to standard therapy in children with moderate to severe bronchiolitis. CLINICAL TRIAL REGISTRATION NUMBER: CTRI/2018/06/014400.

Indexed as

BronchiolitisMagnesium SulfateAcute DiseaseBronchodilator AgentsChildChild, PreschoolHumansInfantNebulizers and VaporizersTreatment OutcomeBronchodilator AgentsMagnesium SulfateBronchiolitisBronchiolitis severity score (BSS)Magnesium sulphate

Identifiers

PMID33772433
PMCPMC7997787
OpenAlexW3138318256

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.