Evidence map›Paper›PMID 33772381›Full record

SynthesisEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2021

Scoliosis and Prognosis-a systematic review regarding patient-specific and radiological predictive factors for curve progression.

Maximilian Lenz, Stavros Oikonomidis, Arne Harland, Philipp Fürnstahl, Mazda Farshad, Jan Bredow, Peer Eysel, Max Joseph Scheyerer

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Can curve characteristics predict severe progression in night-time bracing in adolescent idiopathic scoliosis?European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
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  5. Advanced machine learning model for Cobb angle progression in adolescent idiopathic scoliosis with surface topography: a multicenter, prospective, observational study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Maximilian LenzDepartment for Orthopaedic and Trauma Surgery, Faculty of Medicine, University Hospital of Cologne, Kerpener Str. 62, Joseph-Stelzmann Strasse 24, 50931, Cologne, Germany. maximilian.lenz@uk-koeln.de.ORCID 0000-0002-1176-0166
Stavros OikonomidisDepartment for Orthopaedic and Trauma Surgery, Faculty of Medicine, University Hospital of Cologne, Kerpener Str. 62, Joseph-Stelzmann Strasse 24, 50931, Cologne, Germany.
Arne HarlandDepartment for Orthopaedic and Trauma Surgery, Faculty of Medicine, University Hospital of Cologne, Kerpener Str. 62, Joseph-Stelzmann Strasse 24, 50931, Cologne, Germany.
Philipp FürnstahlDepartment of Orthopaedic Surgery, Balgrist University Hospital, University of Zürich, Forchstrasse 340, Zurich, Switzerland.
Mazda FarshadDepartment of Orthopaedic Surgery, Balgrist University Hospital, University of Zürich, Forchstrasse 340, Zurich, Switzerland.
Jan BredowDepartment for Orthopaedic and Trauma Surgery, Faculty of Medicine, University Hospital of Cologne, Kerpener Str. 62, Joseph-Stelzmann Strasse 24, 50931, Cologne, Germany.
Peer EyselDepartment for Orthopaedic and Trauma Surgery, Faculty of Medicine, University Hospital of Cologne, Kerpener Str. 62, Joseph-Stelzmann Strasse 24, 50931, Cologne, Germany.
Max Joseph ScheyererDepartment for Orthopaedic and Trauma Surgery, Faculty of Medicine, University Hospital of Cologne, Kerpener Str. 62, Joseph-Stelzmann Strasse 24, 50931, Cologne, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionIdiopathic scoliosis, defined as a > 10° curvature of the spine in the frontal plane, is one of the most common spinal deformities. Age, initial curve magnitude and other parameters define whether a scoliotic deformity will progress or not. Still, their interactions and amounts of individual contribution are not fully elaborated and were the aim of this systematic review.

methodsA systematic literature search was conducted in the common databases using MESH terms, searching for predictive factors of curve progression in adolescent idiopathic scoliosis ("adolescent idiopathic scoliosis" OR "ais" OR "idiopathic scoliosis") AND ("predictive factors" OR "progression" OR "curve progression" OR "prediction" OR "prognosis"). The identified and analysed factors of each study were rated to design a top five scale of the most relevant factors.

resultsTwenty-eight investigations with 8255 patients were identified by literature search. Patient-specific risk factors for curve progression from initial curve were age (at diagnosis < 13 years), family history, bone mineral status (< 110 mg/cm DISCUSSION: This systematic review summarised the current state of knowledge as the basis for creation of patient-specific algorithms regarding a risk calculation for a progressive scoliotic deformity. Curve magnitude is the most relevant predictive factor, followed by status of skeletal maturity and curve location.

Indexed as

ScoliosisAdolescentDisease ProgressionHumansPrognosisRadiographyRetrospective StudiesSpineAdolescent idiopathic scoliosisCurve locationCurve progressionRisk factorsSkeletal maturity

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.