Evidence map›Paper›PMID 33772380›Full record

ArticleClinical and experimental medicine2021

Human Cytomegalovirus and Epstein-Barr virus specific immunity in patients with ulcerative colitis.

Rachele Ciccocioppo, Caterina Mengoli, Elena Betti, Giuditta Comolli, Irene Cassaniti, Antonio Piralla, Peter Kruzliak, Martin Caprnda, Lodovica Pozzi, Gino Roberto Corazza and 2 more

Abstract read
PubMed Publisher
In one paragraph

Article in Clinical and experimental medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 4 countries.

Rachele CiccocioppoGastroenterology Unit, Department of Medicine, A.O.U.I. Policlinico G.B. Rossi, University of Verona, Piazzale L.A. Scuro, 10, 37134, Verona, Italy. rachele.ciccocioppo@univr.it.
Caterina MengoliDepartment of Internal Medicine, San Matteo Hospital Foundation, University of Pavia, Pavia, Italy.
Elena BettiDepartment of Internal Medicine, San Matteo Hospital Foundation, University of Pavia, Pavia, Italy.
Giuditta ComolliMolecular Virology Unit, Microbiology and Virology Department, San Matteo Hospital Foundation, Pavia, Italy.
Irene CassanitiMolecular Virology Unit, Microbiology and Virology Department, San Matteo Hospital Foundation, Pavia, Italy.
Antonio PirallaMolecular Virology Unit, Microbiology and Virology Department, San Matteo Hospital Foundation, Pavia, Italy.
Peter Kruzliak2Nd Department of Surgery, Faculty of Medicine, Masaryk University and St. Anne's University Hospital, Pekarska 53, 65691, Brno, Czech Republic. kruzliakpeter@gmail.com.ORCID http://orcid.org/0000-0002-7069-3784
Martin CaprndaFirst Department of Internal Medicine, Faculty of Medicine, Comenius University and University Hospital, Bratislava, Slovakia.
Lodovica PozziDepartment of Internal Medicine, San Matteo Hospital Foundation, University of Pavia, Pavia, Italy.
Gino Roberto CorazzaDepartment of Internal Medicine, San Matteo Hospital Foundation, University of Pavia, Pavia, Italy.
Antonio Di SabatinoDepartment of Internal Medicine, San Matteo Hospital Foundation, University of Pavia, Pavia, Italy.
Fausto BaldantiMolecular Virology Unit, Microbiology and Virology Department, San Matteo Hospital Foundation, Pavia, Italy.
University of Pavia · ITMasaryk University · CZUniversity Hospital Bratislava · SKUniversity Hospital Foundation · CAUniversity of Verona · IT

Funding

Fondazione IRCCS Policlinico San Matteo 08064415
6 · The paper itself

Abstract

Human Cytomegalovirus (HCMV) and Epstein-Barr virus (EBV) are endowed with the ability of establishing lifelong latency in human hosts and reactivating in immunocompromised subjects, including patients suffering from ulcerative colitis (UC). We, therefore, aimed to investigate virus-specific immunity in UC patients. A cohort of 24 UC patients (14 responders and 10 refractory to therapy) and 26 control subjects was prospectively enrolled to undergo virus-specific serology (by ELISA assay) and assessment of both CD4

Indexed as

Case-Control StudiesCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesColitis, UlcerativeCytomegalovirusCytomegalovirus InfectionsDNA, ViralEpstein-Barr Virus InfectionsFemaleHerpesvirus 4, HumanHumansMaleProspective StudiesSteroidsViral LoadDNA, ViralSteroidsAdaptive immunityEpstein-Barr virusHuman CytomegalovirusTherapyUlcerative colitis

Identifiers

PMID33772380
OpenAlexW3136165133

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.