Evidence map›Paper›PMID 33772332›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2021

Preclinical evaluation of [

Narges K Tafreshi, Darpan N Pandya, Christopher J Tichacek, Mikalai M Budzevich, Zhen Wang, Jordan N Reff, Robert W Engelman, David C Boulware, Alberto A Chiappori, Jonathan R Strosberg and 4 more

Abstract read
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Potency and safety of novel [British journal of cancer · 2026
    Article
  5. Macrocyclic and Hydroxamate Ligands forInorganic chemistry · 2026
    Article
  6. Review
  7. Article
  8. Review
  9. Review
  10. Review
  11. Article
  12. Recent advances in the development ofAnalytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2024
    Review
  13. Review
  14. Review
  15. Article
  16. Initial Findings on the Use of [Molecular imaging and radionuclide therapy · 2023
    Article
  17. Review
  18. Radionuclide-based theranostics - a promising strategy for lung cancer.European journal of nuclear medicine and molecular imaging · 2023
    Review
  19. First preclinical evaluation of [EJNMMI radiopharmacy and chemistry · 2023
    Article
  20. Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Narges K TafreshiDepartment of Cancer Physiology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, USA.
Darpan N PandyaDepartment of Radiology, University of Iowa Health Care, Iowa City, IA, USA.
Christopher J TichacekDepartment of Radiation Oncology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, USA.
Mikalai M BudzevichSmall Animal Imaging Laboratory Shared Resource, Tampa, FL, USA.
Zhen WangDepartment of Drug Discovery, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, USA.
Jordan N ReffDepartment of Cancer Physiology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, USA.
Robert W EngelmanDepartment of Pediatrics, Pathology & Cell Biology, University of South Florida, Tampa, FL, USA.
David C BoulwareBiostatistics and Bioinformatics Shared Resource, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, USA.
Alberto A ChiapporiDepartment of Thoracic Oncology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, USA.
Jonathan R StrosbergGastrointestinal Oncology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, USA.
Haitao JiDepartment of Drug Discovery, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, USA.
Thaddeus J WadasDepartment of Radiology, University of Iowa Health Care, Iowa City, IA, USA.
Ghassan El-HaddadDiagnostic Imaging and Interventional Radiology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, USA. Ghassan.ElHaddad@moffitt.org.
David L MorseDepartment of Cancer Physiology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, USA. David.Morse@moffitt.org.ORCID 0000-0002-6006-7528
Moffitt Cancer Center · USUniversity of South Florida · USUniversity of Iowa Health Care · US

Funding

TRANSLATIONAL RESEARCHP30CA076292 · NCI · UNIVERSITY OF SOUTH FLORIDA · PI Christine O'Connell · 1998 to 2026
$93.5M
NCI NIH HHS P30 CA076292
6 · The paper itself

Abstract

purposeThere is significant interest in the development of targeted alpha-particle therapies (TATs) for treatment of solid tumors. The metal chelator-peptide conjugate, DOTA-TATE, loaded with the β-particle emitting radionuclide

methods[

results[

conclusionsThese results suggest significant potential for the clinical translation of [

Indexed as

Lung NeoplasmsOrganometallic CompoundsAnimalsHumansMiceMice, Inbred BALB CMice, SCIDOctreotideRadiopharmaceuticalsTissue DistributionOctreotideOrganometallic CompoundsRadiopharmaceuticals[225Ac]Ac-DOTA-TATE225Ac targeted alpha therapyLung neuroendocrine neoplasms

Identifiers

PMID33772332
PMCPMC12866175
OpenAlexW3135969529

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.