ArticleThe Journal of clinical endocrinology and metabolism2021
Ovarian Reserve Biomarkers and Menstrual Cycle Length in a Prospective Cohort Study.
Article in The Journal of clinical endocrinology and metabolism, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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The trial behind it
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Who cites it
21 citing papers in PubMed, 29 citations in OpenAlex.
- Declines in ovarian reserve associated with ambient ozone exposure: mediating role of lipid profile.Lipids in health and disease · 2026Article
- Relationship between anti-Müllerian hormone concentration in the peripheral blood of women and aneuploid pregnancy.BMC pregnancy and childbirth · 2026Article
- Baseline vagal tone and pain reactivity: linking autonomic function to endogenous pain inhibition in women.Pain reports · 2026Article
- Age at menarche and age-adjusted anti-Müllerian hormone level among women of childbearing age in China.Journal of ovarian research · 2026Article
- Association between menstrual cycle length and ovarian reserve markers and stimulation response: a retrospective cohort study.BMC women's health · 2026Article
- Luteal-phase deficiency and diminished ovarian reserve: a narrative review of interactions and clinical implications.Archives of gynecology and obstetrics · 2026Review
- Determination of the optimal follicle size at the time of trigger in patients with diminished ovarian reserve undergoing ICSI cycle.Journal of ovarian research · 2025Article
- Impact of Tamoxifen on Endometrial Thickness in Women With Thin Endometrium Following Estrogen Therapy During Frozen-Thawed Embryo Transfer.Clinical case reports · 2025Article
- Low anti-müllerian hormone levels increased early pregnancy loss rate in patients undergoing frozen-thawed euploid single blastocyst transfer: a retrospective cohort study.Reproductive biology and endocrinology : RB&E · 2025Article
- Shorter ovarian stimulation is detrimental to fresh embryo transfer outcomes in PCOS women undergoing GnRH antagonist protocol: a retrospective cohort study.Scientific reports · 2025Article
- Inflammation and Ovarian Function in Reproductive-Aged Women.American journal of human biology : the official journal of the Human Biology Council · 2025Article
- Article
- Relationship of length of the estrous cycle to antral follicle number in crossbred beef heifers.Translational animal science · 2024Article
- Menstrual cycle length variation by demographic characteristics from the Apple Women's Health Study.NPJ digital medicine · 2023Article
- The association between menstrual cycle characteristics and cardiometabolic outcomes in later life: a retrospective matched cohort study of 704,743 women from the UK.BMC medicine · 2023Article
- Systemic inflammation and menstrual cycle length in a prospective cohort study.American journal of obstetrics and gynecology · 2023Article
- Low ovarian reserve and risk of miscarriage in pregnancies derived from assisted reproductive technology.Human reproduction open · 2023Article
- Markers of ovarian reserve as predictors of future fertility.Fertility and sterility · 2023Article
- Investigation of the role of X chromosome inactivation and androgen receptor CAG repeat polymorphisms in patients with recurrent pregnancy loss: a prospective case-control study.BMC pregnancy and childbirth · 2022Article
- Menstrual cycle length and modern living: a review.Current opinion in endocrinology, diabetes, and obesity · 2021Review
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
contextWhile age-related changes in menstrual cycle length are well known, it is unclear whether anti-Müllerian (AMH) or other ovarian reserve biomarkers have a direct association with cycle length.
objectiveTo determine the association between biomarkers of ovarian reserve and menstrual cycle length.
methodsSecondary analysis using data from time to conceive (TTC), a prospective time to pregnancy cohort study. The age-independent association between cycle length and biomarkers of ovarian reserve was analyzed using linear mixed and marginal models. Study participants were TTC-enrolled women aged 30-44 years with no history of infertility who were attempting to conceive for <3 months were enrolled. Serum AMH, follicle-stimulating hormone, and inhibin B levels were measured on cycle day 2, 3, or 4. Participants recorded daily menstrual cycle data for ≤4 months. The primary outcome was menstrual cycle length; follicular and luteal phase lengths were secondary outcomes.
resultsMultivariable analysis included 1880 cycles from 632 women. Compared with AMH levels of 1.6 to 3.4 ng/mL, women with AMH <1.6 ng/mL had cycles and follicular phases that were 0.98 (95% CI -1.46, -0.50) and 1.58 days shorter (95% CI -2.53, -0.63), respectively, while women with AMH >8 ng/mL had cycles that were 2.15 days longer (95% CI 1.46, 2.83), follicular phases that were 2 days longer (95% CI 0.77, 3.24), and luteal phases that were 1.80 days longer (95% CI 0.71, 2.88).
conclusionIncreasing AMH levels are associated with longer menstrual cycles due to both a lengthening of the follicular and the luteal phase independent of age.
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