Evidence map›Paper›PMID 33772242›Full record

ReviewNature reviews. Immunology2021

Tissue regulatory T cells: regulatory chameleons.

Andrés R Muñoz-Rojas, Diane Mathis

Open access · greenAbstract readReview
In one paragraph

Review in Nature reviews. Immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 171 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
171citing papers in PubMed, 1 pooled it
14.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

171 citing papers in PubMed, 1 synthesis or guideline pooled it, 256 citations in OpenAlex.

  1. Dynamics and functional heterogeneity of FOXP3+ regulatory T cells in Trypanosoma cruzi infection: a systematic review.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2026
    Pooled it
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  10. Regulatory T cells in the skin: Origin, function, and plasticity.JID innovations : skin science from molecules to population health · 2026
    Review
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  20. Regulatory T cells in cancer and inflammation.Signal transduction and targeted therapy · 2026
    Review

111 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Andrés R Muñoz-RojasDepartment of Immunology, Harvard Medical School, Boston, MA, USA.ORCID http://orcid.org/0000-0002-1251-723X
Diane MathisDepartment of Immunology, Harvard Medical School, Boston, MA, USA. dm@hms.harvard.edu.ORCID http://orcid.org/0000-0002-6110-4626
Brigham and Women's Hospital · US

Funding

Investigating Human Adipocyte HeterogeneityRC2DK116691 · NIDDK · BETH ISRAEL DEACONESS MEDICAL CENTER · PI Orr Ashenberg, Noel P Burtt · 2018 to 2026
$17.8M
Adipose-tissue Tregs: important players in immunological control of metabolismR01DK092541 · NIDDK · HARVARD MEDICAL SCHOOL · PI DIANE J MATHIS · 2011 to 2026
$6.4M
Muscle Tregs in health and diseaseR01AR070334 · NIAMS · HARVARD MEDICAL SCHOOL · PI MATHIS, DIANE J · 2016 to 2025
$3.7M
NIAMS NIH HHS R01 AR070334NIDDK NIH HHS R01 DK092541NIDDK NIH HHS RC2 DK116691
6 · The paper itself

Abstract

The FOXP3

Indexed as

AnimalsFemaleHomeostasisHumansIntra-Abdominal FatMaleMiceModels, ImmunologicalMuscle, SkeletalReceptors, Antigen, T-CellSkinT-Lymphocytes, RegulatoryTranscriptomeReceptors, Antigen, T-Cell

Identifiers

PMID33772242
PMCPMC8403160
OpenAlexW3136492352

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.