Evidence map›Paper›PMID 33772060›Full record

ArticleScientific reports2021

Using carpet plots to analyze transit times of low frequency oscillations in resting state fMRI.

Bradley Fitzgerald, Jinxia Fiona Yao, Thomas M Talavage, Lia M Hocke, Blaise deB Frederick, Yunjie Tong

Abstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Effects of clamping end-tidal CONMR in biomedicine · 2024
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Bradley Fitzgerald *School of Electrical and Computer Engineering, Purdue University, West Lafayette, IN, 47907, USA.
Jinxia Fiona Yao *Weldon School of Biomedical Engineering, Purdue University, 206 S. Martin Jischke Drive, West Lafayette, IN, 47907-2032, USA.
Thomas M TalavageWeldon School of Biomedical Engineering, Purdue University, 206 S. Martin Jischke Drive, West Lafayette, IN, 47907-2032, USA.
Lia M HockeMclean Hospital, Harvard Medical School, Belmont, MA, 02478, USA.
Blaise deB FrederickMclean Hospital, Harvard Medical School, Belmont, MA, 02478, USA.
Yunjie TongWeldon School of Biomedical Engineering, Purdue University, 206 S. Martin Jischke Drive, West Lafayette, IN, 47907-2032, USA. tong61@purdue.edu.

Funding

Multimodal Neuroimaging of Cigarette SmokingK25DA031769 · NIDA · PURDUE UNIVERSITY · PI TONG, YUNJIE · 2013 to 2017
$762k
Probing cerebral hemodynamics in Alzheimer's Disease using novel retrospective delay analysisR21AG070383 · NIA · MCLEAN HOSPITAL · PI HOCKE, LIA MARIA · 2020 to 2020
$410k
A New Multimodal Perfusion Imaging Method Using Concurrent NIRS and fMRIR21DA032746 · NIDA · MCLEAN HOSPITAL · PI FREDERICK, BLAISE DEBONNEVAL · 2012 to 2013
$398k
NIA NIH HHS R21 AG070383NIDA NIH HHS K25 DA031769NIDA NIH HHS R21 DA032746
6 · The paper itself

Abstract

A "carpet plot" is a 2-dimensional plot (time vs. voxel) of scaled fMRI voxel intensity values. Low frequency oscillations (LFOs) can be successfully identified from BOLD fMRI and used to study characteristics of neuronal and physiological activity. Here, we evaluate the use of carpet plots paired with a developed slope-detection algorithm as a means to study LFOs in resting state fMRI (rs-fMRI) data with the help of dynamic susceptibility contrast (DSC) MRI data. Carpet plots were constructed by ordering voxels according to signal delay time for each voxel. The slope-detection algorithm was used to identify and calculate propagation times, or "transit times", of tilted vertical edges across which a sudden signal change was observed. We aim to show that this metric has applications in understanding LFOs in fMRI data, possibly reflecting changes in blood flow speed during the scan, and for evaluating alternative blood-tracking contrast agents such as inhaled CO

Indexed as

AdultBlood Flow VelocityBrainCardiovascular SystemCerebrovascular CirculationHemodynamicsHumansMagnetic Resonance ImagingOxygenRegression AnalysisOxygen

Identifiers

PMID33772060
PMCPMC7998022

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.