ArticleNature communications2021
Enzymatic enhancing of triplet-triplet annihilation upconversion by breaking oxygen quenching for background-free biological sensing.
Article in Nature communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed, 98 citations in OpenAlex.
- Article
- Article
- Upconversion Nanoparticle-Based Luminescence DNA Sensor on Porous Silicon Substrate.Biosensors · 2026Article
- Homomolecular Photon Upconversion in a Perylene-Decorated Iron(III) Complex.Journal of the American Chemical Society · 2025Article
- Near-Infrared to Visible Photon Upconversion with Gold Quantum Rods and Aqueous Photo-Driven Polymerization.Journal of the American Chemical Society · 2025Article
- Cascade upconversion: a strategy enabling four-photon lithography in weak light intensity.Nature communications · 2025Article
- Review
- Temperature Sensing in Agarose/Silk Fibroin Translucent Hydrogels: Preparation of an Environment for Long-Term Observation.Nanomaterials (Basel, Switzerland) · 2025Article
- Separating triplet exciton diffusion from triplet-triplet annihilation by the introduction of a mediator.Chemical science · 2025Article
- Crystalline organic monoliths with bicontinuous porosity.Chemical science · 2024Article
- Donor-acceptor bulk-heterojunction sensitizer for efficient solid-state infrared-to-visible photon up-conversion.Nature communications · 2024Article
- Unlocking Arene Phosphorescence in Bismuth-Organic Materials.Inorganic chemistry · 2024Article
- Solar overall water-splitting by a spin-hybrid all-organic semiconductor.Nature communications · 2024Article
- Triplet-triplet annihilation photon upconversion-mediated photochemical reactions.Nature reviews. Chemistry · 2024Review
- Molecular near-infrared triplet-triplet annihilation upconversion with eigen oxygen immunity.Nature communications · 2024Article
- Water-Dispersible and Biocompatible Polymer-Based Organic Upconversion Nanoparticles for Transdermal Delivery.Biomaterials research · 2024Article
- Ultra-Small Air-Stable Triplet-Triplet Annihilation Upconversion Nanoparticles for Anti-Stokes Time-Resolved Imaging.Angewandte Chemie (International ed. in English) · 2023Article
- Bulky Substituents Promote Triplet-Triplet Annihilation Over Triplet Excimer Formation in Naphthalene Derivatives.Journal of the American Chemical Society · 2023Article
- Recent Progress in Photonic Upconversion Materials for Organic Lanthanide Complexes.Materials (Basel, Switzerland) · 2023Review
- Bodipy Dimer for Enhancing Triplet-Triplet Annihilation Upconversion Performance.Molecules (Basel, Switzerland) · 2023Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Triplet-triplet annihilation upconversion nanoparticles have attracted considerable interest due to their promises in organic chemistry, solar energy harvesting and several biological applications. However, triplet-triplet annihilation upconversion in aqueous solutions is challenging due to sensitivity to oxygen, hindering its biological applications under ambient atmosphere. Herein, we report a simple enzymatic strategy to overcome oxygen-induced triplet-triplet annihilation upconversion quenching. This strategy stems from a glucose oxidase catalyzed glucose oxidation reaction, which enables rapid oxygen depletion to turn on upconversion in the aqueous solution. Furthermore, self-standing upconversion biological sensors of such nanoparticles are developed to detect glucose and measure the activity of enzymes related to glucose metabolism in a highly specific, sensitive and background-free manner. This study not only overcomes the key roadblock for applications of triplet-triplet annihilation upconversion nanoparticles in aqueous solutions, it also establishes the proof-of-concept to develop triplet-triplet annihilation upconversion nanoparticles as background free self-standing biological sensors.
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