ArticleOptometry and vision science : official publication of the American Academy of Optometry2021
American Academy of Optometry Microbial Keratitis Think Tank.
Article in Optometry and vision science : official publication of the American Academy of Optometry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 36 citations in OpenAlex.
- Contact Lens-Associated Ocular Surface and Corneal Disorders.Methods and protocols · 2026Review
- Antibacterial Potential of Lucilia sericata (Meigen, 1826) (Diptera: Calliphoridae) Maggot Excretions/Secretions in Presence of Human Tear Fluid.Neotropical entomology · 2025Article
- Development of a text message intervention designed to promote safe contact lens wear.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2025Article
- Methamphetamine-Associated Corneal Ulcer: Case Report.Reports (MDPI) · 2025Article
- Comparison of Recurrent and Naïve Keratitis in a Cohort of 1303 Patients.Journal of clinical medicine · 2025Article
- Parasitological and microbiological assessment of contact lens storage cases: a survey of asymptomatic lens student wearers from five medical specialties in Tunisia, North Africa.BMC infectious diseases · 2025Article
- Exploring Symptom Experience and Management Strategies Among Patients with Corneal Ulcers Based on Symptom Management Theory: A Qualitative Study.Patient preference and adherence · 2025Article
- Biocidal Efficacies of Contact Lens Disinfecting Solutions Against International Organization for Standardization (ISO) Compendial Organisms.Clinical ophthalmology (Auckland, N.Z.) · 2024Article
- How Can We Better Inform Patients of the Importance of Contact Lens Compliance?: Current Perspectives.Clinical optometry · 2024Review
- Novel Peptides with Dual Properties for TreatingBiomolecules · 2023Article
- Early treatment of corneal abrasions and ulcers-estimating clinical and economic outcomes.The Lancet regional health. Southeast Asia · 2022Article
- Trends in Infectious Keratitis in Taiwan: An Update on Predisposing Factors, Microbiological and Antibiotic Susceptibility Patterns.Diagnostics (Basel, Switzerland) · 2022Article
- First Report of a Case of Ocular Infection Caused byPathogens (Basel, Switzerland) · 2021Article
- Improved Topical Ophthalmic Natamycin Suspension for the Treatment of Fungal Keratitis.Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and TherapeuticsArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors at 15 institutions in 3 countries.
Funding
Abstract
significanceThink Tank 2019 affirmed that the rate of infection associated with contact lenses has not changed in several decades. Also, there is a trend toward more serious infections associated with Acanthamoeba and fungi. The growing use of contact lenses in children demands our attention with surveillance and case-control studies. PURPOSE: The American Academy of Optometry (AAO) gathered researchers and key opinion leaders from around the world to discuss contact lens-associated microbial keratitis at the 2019 AAO Annual Meeting.
methodsExperts presented within four sessions. Session 1 covered the epidemiology of microbial keratitis, pathogenesis of Pseudomonas aeruginosa, and the role of lens care systems and storage cases in corneal disease. Session 2 covered nonbacterial forms of keratitis in contact lens wearers. Session 3 covered future needs, challenges, and research questions in relation to microbial keratitis in youth and myopia control, microbiome, antimicrobial surfaces, and genetic susceptibility. Session 4 covered compliance and communication imperatives.
resultsThe absolute rate of microbial keratitis has remained very consistent for three decades despite new technologies, and extended wear significantly increases the risk. Improved oxygen delivery afforded by silicone hydrogel lenses has not impacted the rates, and although the introduction of daily disposable lenses has minimized the risk of severe disease, there is no consistent evidence that they have altered the overall rate of microbial keratitis. Overnight orthokeratology lenses may increase the risk of microbial keratitis, especially secondary to Acanthamoeba, in children. Compliance remains a concern and a significant risk factor for disease. New insights into host microbiome and genetic susceptibility may uncover new theories. More studies such as case-control designs suited for rare diseases and registries are needed.
conclusionsThe first annual AAO Think Tank acknowledged that the risk of microbial keratitis has not decreased over decades, despite innovation. Important questions and research directions remain.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.