ArticleProceedings of the National Academy of Sciences of the United States of America2021
DNA hypomethylation in tetraploid rice potentiates stress-responsive gene expression for salt tolerance.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers.
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75 citing papers in PubMed, 139 citations in OpenAlex.
- Homoeologous exchange-associated ABA catabolism rewiring contributes to salinity tolerance in a synthetic tetraploid rice.Plant cell reports · 2026Article
- Epigenetic regulation and ROS signaling in plant stress adaptation: an integrated framework.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Review
- Convergence and divergence of DNA methylation and gene expression patterns in neopolyploid Arabidopsis kamchatica.Nature communications · 2026Article
- The dynamic landscape of plant DNA demethylation: mechanisms, functions, and environmental responses.Plant cell reports · 2026Review
- Large-scale genomic analysis reveals the origin and evolution of Glutathione S-transferases (GSTs) in plants.BMC genomics · 2026Article
- Polyploidy: A macromutational force pushing bioeconomic developments.Proceedings of the National Academy of Sciences of the United States of America · 2026Review
- Polyploidization enhances plant resistance toHorticulture research · 2026Article
- Aneuploidy confers environmentally robust higher evolvability than euploidy in a synthetic allotetraploid wheat.Science advances · 2026Article
- Polyploidy and plant resilience to environmental stresses: Molecular mechanisms and future applications.Plant communications · 2026Review
- Transcriptomic and DNA methylation insights into polyploidy-enhanced heat tolerance in rice (Oryza sativa L.).Plant physiology · 2026Article
- Polyploidy and zinc nanoparticles enhanced cadmium tolerance by regulating antioxidants and transport proteins.Plant cell reports · 2026Article
- Frequent origins and unidirectional gene-flow sustain cytotype coexistence in a mixed-ploidy species.BMC plant biology · 2026Article
- Autopolyploidization-Induced Chromatin Remodeling Regulates Leaf Size Variation in Brassica rapa.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- A comparative study of phyllostachys edulis and its dwarf variant phyllostachys edulis 'Tubaeformis' at the anatomical, transcriptomic, and DNA methylation levels.Frontiers in plant science · 2026Article
- Harnessing polyploidy and nitric oxide for improved arsenic tolerance in Oryza sativa.BMC plant biology · 2025Article
- Epigenetic Regulation of Salt Stress Responses in Rice: Mechanisms and Prospects for Enhancing Tolerance.Epigenomes · 2025Review
- Synthetic Polyploidisation Enhances Fusarium graminearum Tolerance in Wheat by Reshaping the Transcriptome and Strengthening the Microbiome.Plant biotechnology journal · 2025Article
- Article
- DNA methylation changes in Medicago sativa under salt-alkaline stress and the function of 5-azacytidine in enhancing stress tolerance.BMC plant biology · 2025Article
- Rootstock of distant hybrid activates transcription factors of scion cultivar to promote growth and yield in walnut.Plant biotechnology journal · 2025Article
15 more citing papers are in PubMed but not listed here.
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Authors and funding
7 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Polyploidy is a prominent feature for genome evolution in many animals and all flowering plants. Plant polyploids often show enhanced fitness in diverse and extreme environments, but the molecular basis for this remains elusive. Soil salinity presents challenges for many plants including agricultural crops. Here we report that salt tolerance is enhanced in tetraploid rice through lower sodium uptake and correlates with epigenetic regulation of jasmonic acid (JA)-related genes. Polyploidy induces DNA hypomethylation and potentiates genomic loci coexistent with many stress-responsive genes, which are generally associated with proximal transposable elements (TEs). Under salt stress, the stress-responsive genes including those in the JA pathway are more rapidly induced and expressed at higher levels in tetraploid than in diploid rice, which is concurrent with increased jasmonoyl isoleucine (JA-Ile) content and JA signaling to confer stress tolerance. After stress, elevated expression of stress-responsive genes in tetraploid rice can induce hypermethylation and suppression of the TEs adjacent to stress-responsive genes. These induced responses are reproducible in a recurring round of salt stress and shared between two
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