Evidence map›Paper›PMID 33771893›Full record

ArticleJournal for immunotherapy of cancer2021

When steroids are not enough in immune-related hepatitis: current clinical challenges discussed on the basis of a case report.

Marie-Léa Gauci, Barouyr Baroudjian, Celeste Lebbe, Olivier Roux

Open access · goldAbstract readComment
In one paragraph

Article in Journal for immunotherapy of cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Marie-Léa GauciU976, INSERM, Paris, Île-de-France, France marie-lea.gauci@aphp.fr.ORCID 0000-0003-3081-9810
Barouyr BaroudjianAP-HP, Département de Dermatologie, Hôpital Saint-Louis, Paris, Île-de-France, France.
Celeste LebbeU976, INSERM, Paris, Île-de-France, France.
Olivier RouxService d'hépatologie et réanimation hépatique, DMU DIGEST, AP-HP Nord, Hôpital Beaujon, Clichy, France.
Inserm · FRAssistance Publique – Hôpitaux de Paris · FRHôpital Beaujon · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immune-related hepatitis (IRH) is a frequent but poorly understood immune-related adverse event and its frequency increases since the use of combination therapy in several cancer types. Therefore, there is an urgent need to develop adapted guidelines to manage IRH.In the present letter, based on Ziogas

Indexed as

HepatitisNeoplasmsHumansImmunosuppressive AgentsImmunotherapySteroidsImmunosuppressive AgentsSteroidsimmunotherapymelanoma

Identifiers

PMID33771893
PMCPMC7996650
OpenAlexW3136444323

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.