Evidence map›Paper›PMID 33771871›Full record

ArticleScience advances2021

Loss of Ftsj1 perturbs codon-specific translation efficiency in the brain and is associated with X-linked intellectual disability.

Y Nagayoshi, T Chujo, S Hirata, H Nakatsuka, C-W Chen, M Takakura, K Miyauchi, Y Ikeuchi, B C Carlyle, R R Kitchen and 10 more

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed
3.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 68 citations in OpenAlex.

  1. Article
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  6. Journal of gastrointestinal oncology · 2026
    Article
  7. RNA modification systems as therapeutic targets.Nature reviews. Drug discovery · 2026
    Review
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  10. Article
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  14. Article
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  17. Article
  18. Autonomous ribosome biogenesis in vitro.Nature communications · 2025
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 7 institutions in 2 countries.

Y NagayoshiDepartment of Molecular Physiology, Faculty of Life Sciences, Kumamoto University, Kumamoto 860-8556, Japan.ORCID 0000-0003-2971-5803
T ChujoDepartment of Molecular Physiology, Faculty of Life Sciences, Kumamoto University, Kumamoto 860-8556, Japan.ORCID 0000-0003-2393-5776
S HirataDepartment of Chemistry and Biotechnology, School of Engineering, The University of Tokyo, Tokyo 113-8656, Japan.
H NakatsukaDepartment of Human Intelligence Systems, Graduate School of Life Science and Systems Engineering, Kyushu Institute of Technology, Kitakyushu 808-0196, Japan.
C-W ChenLaboratory for Protein Conformation Diseases, RIKEN Brain Science Institute, Saitama 351-0198, Japan.ORCID 0000-0002-1214-4058
M TakakuraDepartment of Chemistry and Biotechnology, School of Engineering, The University of Tokyo, Tokyo 113-8656, Japan.ORCID 0000-0003-2187-5239
K MiyauchiDepartment of Chemistry and Biotechnology, School of Engineering, The University of Tokyo, Tokyo 113-8656, Japan.ORCID 0000-0002-4075-7660
Y IkeuchiDepartment of Chemistry and Biotechnology, School of Engineering, The University of Tokyo, Tokyo 113-8656, Japan.ORCID 0000-0002-2829-3840
B C CarlyleDepartment of Psychiatry, Yale University School of Medicine, New Haven, CT 06520, USA.ORCID 0000-0003-1491-3217
R R KitchenDepartment of Psychiatry, Yale University School of Medicine, New Haven, CT 06520, USA.ORCID 0000-0003-1443-8559
T SuzukiDepartment of Chemistry and Biotechnology, School of Engineering, The University of Tokyo, Tokyo 113-8656, Japan.ORCID 0000-0002-9731-1731
F KatsuokaDepartment of Integrative Genomics, Tohoku Medical Megabank Organization, Tohoku University, Sendai 980-8573, Japan.ORCID 0000-0003-0939-7887
M YamamotoDepartment of Integrative Genomics, Tohoku Medical Megabank Organization, Tohoku University, Sendai 980-8573, Japan.ORCID 0000-0002-9073-9436
Y GotoDepartment of Mental Retardation and Birth Defect Research, National Institute of Neurology, NCNP, Tokyo 187-8551, Japan.ORCID 0000-0002-2426-9739
M TanakaLaboratory for Protein Conformation Diseases, RIKEN Brain Science Institute, Saitama 351-0198, Japan.ORCID 0000-0002-2994-7703
K NatsumeDepartment of Human Intelligence Systems, Graduate School of Life Science and Systems Engineering, Kyushu Institute of Technology, Kitakyushu 808-0196, Japan.ORCID 0000-0003-2529-4466
A C NairnDepartment of Psychiatry, Yale University School of Medicine, New Haven, CT 06520, USA.ORCID 0000-0002-7075-0195
T SuzukiDepartment of Chemistry and Biotechnology, School of Engineering, The University of Tokyo, Tokyo 113-8656, Japan.
K TomizawaDepartment of Molecular Physiology, Faculty of Life Sciences, Kumamoto University, Kumamoto 860-8556, Japan. tomikt@kumamoto-u.ac.jp fanyan.wei.d3@tohoku.ac.jp.ORCID 0000-0002-5663-2627
F-Y WeiDepartment of Molecular Physiology, Faculty of Life Sciences, Kumamoto University, Kumamoto 860-8556, Japan. tomikt@kumamoto-u.ac.jp fanyan.wei.d3@tohoku.ac.jp.ORCID 0000-0002-4843-724X
The University of Tokyo · JPKumamoto University · JPTohoku University · JPYale University · USKyushu Institute of Technology · JPRIKEN Center for Brain Science · JPNational Center of Neurology and Psychiatry · JP

Funding

Yale/NIDA Neuroproteomics Research CenterP30DA018343 · NIDA · YALE UNIVERSITY · PI Marina R Picciotto · 2004 to 2026
$37.1M
Yale Alzheimer Disease Research CenterP30AG066508 · NIA · YALE UNIVERSITY · PI STEPHEN M STRITTMATTER · 2020 to 2026
$30.2M
Yale Alzheimer Disease Research CenterP50AG047270 · NIA · YALE UNIVERSITY · PI STRITTMATTER, STEPHEN M · 2015 to 2019
$8.3M
The Massachusetts and Yale ADRC Collaborative Proteomic Biofluid Biomarker Discovery ProgramR01AG062306 · NIA · MASSACHUSETTS GENERAL HOSPITAL · PI ARNOLD, STEVEN E, CARLYLE, BECKY CATHERINE · 2018 to 2022
$3.5M
NIA NIH HHS P30 AG066508NIA NIH HHS P50 AG047270NIA NIH HHS R01 AG062306NIDA NIH HHS P30 DA018343
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID33771871
PMCPMC7997516
OpenAlexW3136149877

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.