Evidence map›Paper›PMID 33771822›Full record

ArticleBMJ open2021

Predictors of controlled prescription drug non-medical and lifetime use among patients accessing public mental health services in Uganda: a cross-sectional study.

Pakoyo Fadhiru Kamba, John Mulangwa, Peter Kageni, Sulah Balikuna, Allan Kengo, Brian Byamah Mutamba, Nelson Sewankambo, Richard Odoi Adome, Pauline Byakika-Kibwika

Abstract read
In one paragraph

Article in BMJ open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Pakoyo Fadhiru KambaDepartment of Pharmacy, College of Health Sciences, Makerere University, Kampala, Uganda kambaf2000@yahoo.com.ORCID http://orcid.org/0000-0001-5169-0767
John MulangwaDepartment of Pharmacy, College of Health Sciences, Makerere University, Kampala, Uganda.
Peter KageniDepartment of Pharmacy, College of Health Sciences, Makerere University, Kampala, Uganda.
Sulah BalikunaDepartment of Pharmacy, College of Health Sciences, Makerere University, Kampala, Uganda.
Allan KengoDepartment of Pharmacology, Faculty of Medicine, Gulu University, Gulu, Uganda.
Brian Byamah MutambaDepartment of Psychiatry, Butabika National Referral Mental Hospital, Kampala, Uganda.
Nelson SewankamboDepartment of Internal Medicine, College of Health Sciences, Makerere University, Kampala, Uganda.
Richard Odoi AdomeDepartment of Pharmacy, College of Health Sciences, Makerere University, Kampala, Uganda.
Pauline Byakika-KibwikaDepartment of Internal Medicine, College of Health Sciences, Makerere University, Kampala, Uganda.

Funding

NURTURE:Research Training and Mentoring Program for Career Development of Faculty at Makerere University College of Health SciencesD43TW010132 · FIC · MAKERERE UNIVERSITY COLLEGE OF HEALTH SCIENCES · PI SEWANKAMBO, NELSON K · 2015 to 2019
$4.3M
FIC NIH HHS D43 TW010132
6 · The paper itself

Abstract

objectivesWe determined the prevalence of controlled prescription drug (CPD) non-medical and lifetime use and their predictors among patients at three public psychiatric clinics in Uganda to identify missed care opportunities, enhanced screening priorities, and drug control needs.

methodsA cross-sectional survey of 1275 patients was performed from November to December 2018. Interviewer-administered semi-structured questionnaires, desk review guide and urine drug assays were employed. Questionnaire recorded CPD non-medical and illicit drug use history from patients' files, CPD lifetime use and risk factors. Desk review guide recorded recently prescribed drugs in patients' files to corroborate with urine assays. Predictors were analysed by multivariate logistic regression.

resultsFrom desk review, 145 (11.4%) patients had history of CPD non-medical use and 36 (2.8%) had used illicit drugs. Of 988 patients who provided urine, 166 (16.8%) self-medicated CPDs, particularly benzodiazepines while 12 (1.2%) used illicit drugs. Of those with drug-positive urine, 123 (69.1%) had no documented history of CPD non-medical and illicit drug use. Being an inpatient (OR=10.90, p<0.001) was independently associated with CPD non-medical use. Additionally, being an inpatient (OR=8.29, p<0.001) and tobacco consumption (OR=1.85, p=0.041) were associated with CPD non-medical and illicit drug use combined. Among participants, 119 (9.3%) reported CPD lifetime use, and this was independently associated with education level (OR=2.71, p<0.001) and history of treatment for substance abuse (OR=2.08, p=0.018).

conclusionsCPD non-medical use is common among Uganda's psychiatric patients, and more prevalent than illicit drug use. Rapid diagnostic assays may be needed in psychiatric care in resource limited settings. It is necessary to assess how CPD non-medical use impacts mental care outcomes and patient safety. High risk groups like inpatients and tobacco consumers should be prioritised in psychiatric screening.

Indexed as

Illicit DrugsMental Health ServicesPrescription DrugsSubstance-Related DisordersCross-Sectional StudiesHumansUgandaIllicit DrugsPrescription Drugsclinical pharmacologyclinical physiologyforensic medicinemental healthpsychiatrysubstance misuse

Identifiers

PMID33771822
PMCPMC8006833

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.