Evidence map›Paper›PMID 33771764›Full record

ArticleBMJ open diabetes research & care2021

Incidence and pathophysiology of diabetes in South Asian adults living in India and Pakistan compared with US blacks and whites.

K M Venkat Narayan, Dimple Kondal, Natalie Daya, Unjali P Gujral, Deepa Mohan, Shivani A Patel, Roopa Shivashankar, Ranjit Mohan Anjana, Lisa R Staimez, Mohammed K Ali and 6 more

Open access · goldAbstract read
In one paragraph

Article in BMJ open diabetes research & care, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 2 pooled it
5.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 2 syntheses or guidelines pooled it, 55 citations in OpenAlex.

  1. Pooled it
  2. Meta-analysis of the Relationship between Type 2 Diabetes Mellitus and Renal Cancer Risk.Endocrine, metabolic & immune disorders drug targets · 2024
    Pooled it
  3. Trial
  4. Trial
  5. Review
  6. Review
  7. Perspectives and Beliefs Surrounding Postpartum Care and Physical Activity of South Asian Immigrant Women in Canada.The Canadian journal of nursing research = Revue canadienne de recherche en sciences infirmieres · 2026
    Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Review
  14. Phenotypic and Genetic Diversity in Diabetes Across Populations.The Journal of clinical endocrinology and metabolism · 2025
    Review
  15. Review
  16. Heterogeneity of type 2 diabetes in rural India.Frontiers in endocrinology · 2025
    Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors at 6 institutions in 3 countries.

K M Venkat NarayanRollins School of Public Health, Atlanta, Georgia, USA knaraya@emory.edu.ORCID 0000-0001-8621-5405
Dimple KondalPublic Health Foundation of India, New Delhi, Delhi, India.
Natalie DayaJohns Hopkins Bloomberg School of Public Health Center for Teaching and Learning, Baltimore, Maryland, USA.
Unjali P GujralRollins School of Public Health, Atlanta, Georgia, USA.ORCID 0000-0002-0352-813X
Deepa MohanMadras Diabetes Research Foundation, Chennai, Tamil Nadu, India.
Shivani A PatelRollins School of Public Health, Atlanta, Georgia, USA.
Roopa ShivashankarPublic Health Foundation of India, New Delhi, Delhi, India.
Ranjit Mohan AnjanaMadras Diabetes Research Foundation, Chennai, Tamil Nadu, India.ORCID 0000-0002-4843-1374
Lisa R StaimezRollins School of Public Health, Atlanta, Georgia, USA.ORCID 0000-0002-2818-1187
Mohammed K AliRollins School of Public Health, Atlanta, Georgia, USA.
Howard H ChangRollins School of Public Health, Atlanta, Georgia, USA.
Masood KadirAga Khan University, Karachi, Pakistan.
Dorairaj PrabhakaranPublic Health Foundation of India, New Delhi, Delhi, India.
Elizabeth SelvinDepartment of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland, USA.ORCID 0000-0001-6923-7151
Viswanathan MohanMadras Diabetes Research Foundation, Chennai, Tamil Nadu, India.ORCID 0000-0001-5038-6210
Nikhil TandonAll India Institute of Medical Sciences, New Delhi, Delhi, India.ORCID 0000-0003-4604-1986
Georgia Department of Public Health · USMadras Diabetes Research Foundation · INPublic Health Foundation of India · INJohns Hopkins University · USAga Khan University · PKAll India Institute of Medical Sciences · IN

Funding

Implementing a Maternal health and PRegnancy Outcomes Vision for Everyone (IMPROVE)UL1TR002378 · NCATS · EMORY UNIVERSITY · PI Andres J Garcia, Elizabeth O. Ofili · 2017 to 2026
$92.1M
Institutional Career Development CoreKL2TR002381 · NCATS · EMORY UNIVERSITY · PI HENRY M BLUMBERG, Anandi Nayan Sheth · 2017 to 2026
$14.1M
Translational Research Core - Engagement and Behavior ChangeP30DK111024 · NIDDK · EMORY UNIVERSITY · PI Mohammed Kumail Ali · 2016 to 2026
$13.4M
Neuro HPA Project 1U54AG062334 · NIA · EMORY UNIVERSITY · PI Ighovwerha Ofotokun · 2018 to 2026
$12.2M
Worksite Lifestyle Program for Reducing Diabetes and Cardiovascular Risk in IndiaR01HL125442 · NHLBI · EMORY UNIVERSITY · PI PRABHAKARAN, DORAIRAJ, WEBER, MARY BETH · 2015 to 2019
$3.3M
Integrated Tracking, Referral, and Algorithmic Management (I-TREC) System for Hypertension and DiabetesU01HL138635 · NHLBI · ALL-INDIA INSTITUTE OF MEDICAL SCIENCES · PI TANDON, NIKHIL · 2017 to 2021
$1.3M
Interdisciplinary research training: NCD epidemiology and prevention in IndiaD43HD065249 · NICHD · CENTRE FOR CHRONIC DISEASE CONTROL · PI NARAYAN, KABAYAM M VENKAT, TANDON, NIKHIL · 2009 to 2013
$1.2M
Health systems & implementation sciences institute for NCDs in SoAsia & LatinAmD43TW009135 · FIC · EMORY UNIVERSITY · PI LOZANO, RAFAEL, NARAYAN, KABAYAM M VENKAT · 2012 to 2016
$1.1M
Research and Mentoring in the Clinical Epidemiology of Cardiovascular Disease and Type 2 DiabetesK24HL152440 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI SELVIN, ELIZABETH · 2020 to 2024
$612k
FIC NIH HHS D43 TW009135NCATS NIH HHS KL2 TR002381NCATS NIH HHS UL1 TR002378NHLBI NIH HHS HHSN268200900026CNHLBI NIH HHS HHSN268201700001CNHLBI NIH HHS HHSN268201700001INHLBI NIH HHS HHSN268201700002CNHLBI NIH HHS HHSN268201700002INHLBI NIH HHS HHSN268201700003CNHLBI NIH HHS HHSN268201700003INHLBI NIH HHS HHSN268201700004CNHLBI NIH HHS HHSN268201700004INHLBI NIH HHS HHSN268201700005CNHLBI NIH HHS HHSN268201700005INHLBI NIH HHS K24 HL152440NHLBI NIH HHS R01 HL125442NHLBI NIH HHS U01 HL138635NIA NIH HHS U54 AG062334NICHD NIH HHS D43 HD065249NIDDK NIH HHS P30 DK111024Wellcome TrustWellcome Trust WT084754/Z/08/A
6 · The paper itself

Abstract

introductionWe compared diabetes incidence in South Asians aged ≥45 years in urban India (Chennai and Delhi) and Pakistan (Karachi), two low-income and middle-income countries undergoing rapid transition, with blacks and whites in the US, a high-income country. RESEARCH DESIGN AND

methodsWe computed age-specific, sex-specific and body mass index (BMI)-specific diabetes incidence from the prospective Center for Cardiometabolic Risk Reduction in South Asia Study (n=3136) and the Atherosclerosis Risk in Communities Study (blacks, n=3059; whites, n=9924). We assessed factors associated with incident diabetes using Cox proportional hazards regression.

resultsSouth Asians have lower BMI and waist circumference than blacks and whites (median BMI, kg/m

conclusionsSouth Asian adults have lower BMI and are less insulin resistant than US blacks and whites, but have higher diabetes incidence than US whites, especially in subgroups without obesity. Factors other than insulin resistance (ie, insulin secretion) may play an important role in the natural history of diabetes in South Asians.

Indexed as

Black or African AmericanDiabetes MellitusAdultAsian PeopleFemaleHumansIncidenceIndiaMalePakistanProspective StudiesRisk Factorsdiabetes mellitusepidemiologyethnic groupsIndiatype 2

Identifiers

PMID33771764
PMCPMC8006839
OpenAlexW3136889592

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.