Evidence map›Paper›PMID 33771374›Full record

ArticleInternational dental journal2021

Changes in Antibiotic Prescription After Tooth Extraction: A Population-Based Study from 2002 to 2018.

Yoon Young Choi, Kyeong Hee Lee

Abstract read
In one paragraph

Article in International dental journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
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2citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

2 authors.

Yoon Young ChoiArtificial Intelligence Big Data Medical Center, Yonsei University Wonju College of Medicine, Wonju, Korea.
Kyeong Hee LeeDepartment of Dental Hygiene, College of Bioecological Health, Shinhan University, Uijeongbu, Korea. Electronic address: khlee@shinhan.ac.kr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveMicrobial resistance due to antibiotic misuse is a worldwide problem. This study aimed to examine the trends in antibiotic prescription after tooth extraction in Korea.

methodsFrom the database of National Health Insurance Sharing Service, patients who underwent tooth extraction from 2002 to 2018 were selected as subjects, and 10% of them were selected via stratified sampling based on sex and age. Overall, 15,838,529 cases were observed for annual antibiotic prescription and broad-spectrum antibiotic prescription patterns. Additionally, standardized annual antibiotic use was calculated using a defined daily dose.

resultsPrescriptions were issued in 13,429,770 (84.8%) of the tooth extraction cases, of which 12,179,185 (90.7%) included antibiotics. Logistic regression analysis revealed that the likelihood of prescribing antibiotics after tooth extraction decreased in 2003 compared to 2002 (odds ratio, 0.95) but increased from 2004 to 2018. In the case of the broad-spectrum antibiotic prescription rate, there was no clear trend between 2002 and 2012 (odds ratio, 0.89-1.07); however, over the last 5 years, the likelihood of broad-spectrum antibiotic prescription has steadily increased. The value of antibiotics based on the defined daily dose of 1000 patients per day was calculated to be 4.39 in 2002, exhibiting a steady increase later and reaching 6.97 in 2018, whereas that of broad-spectrum antibiotics was 1.68 in 2002 and has since been on the rise; the highest was 3.82 in 2018.

conclusionsAntibiotic use after tooth extraction increased over the last 17 years; additionally, the rate of prescribing broad-spectrum antibiotics has increased over the last 5 years.

Indexed as

Anti-Bacterial AgentsDrug PrescriptionsHumansOdds RatioPractice Patterns, Dentists'Tooth ExtractionAnti-Bacterial AgentsAntibacterial agentsAntibiotic resistanceBroad-spectrum antibioticsPrescriptionsTooth extraction

Identifiers

PMID33771374
PMCPMC9275312

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.